Antifungal activity of thiosemicarbazones, bis (thiosemicarbazones), and their metal complexes

K Bajaj, RM Buchanan, CA Grapperhaus - Journal of Inorganic …, 2021 - Elsevier
Fungi are ubiquitous in nature, and typically cause little or no environmental or pathogenic
damage to their plant, animal, and human hosts. However, a small but growing number of …

A review on development of bio-active thiosemicarbazide derivatives: Recent advances

PT Acharya, ZA Bhavsar, DJ Jethava, DB Patel… - Journal of Molecular …, 2021 - Elsevier
There has been substantial attention in the expansion of new thiosemicarbazide derivatives
with diverse biological activities in recent years. Therefore, many scientists have prepared …

Design, synthesis, and characterization of novel iron chelators: Structure− activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3 …

DS Kalinowski, Y Yu, PC Sharpe, M Islam… - Journal of medicinal …, 2007 - ACS Publications
Previously, we demonstrated that the potent antiproliferative activity of the di-2-pyridylketone
thiosemicarbazone (DpT) series of Fe chelators was due to their ability to induce Fe …

Synthesis, cytotoxic and antimalarial activities of benzoyl thiosemicarbazone analogs of isoquinoline and related compounds

R Pingaew, S Prachayasittikul, S Ruchirawat - Molecules, 2010 - mdpi.com
Thiosemicarbazone analogs of papaveraldine and related compounds 1–6 were
synthesized and evaluated for cytotoxic and antimalarial activities. The cytotoxic activity was …

Synthesis crystal structure of 2-methoxybenzoylhydrazones and evaluation of their α-glucosidase and urease inhibition potential

M Taha, NH Ismail, MS Baharudin, S Lalani… - Medicinal Chemistry …, 2015 - Springer
Compounds 1–30 showed varying degree of α-glucosidase inhibition with IC 50 values
ranging between 187 and 420 μ M. Compounds 1, 2, 3, 6, 8, 12, and 4 (IC 50= 187.7±3.05 …

Structural studies and investigation on the activity of imidazole-derived thiosemicarbazones and hydrazones against crop-related fungi

DC Reis, AAR Despaigne, JGD Silva, NF Silva… - Molecules, 2013 - mdpi.com
New imidazole derived thiosemicarbazones and hydrazones were prepared by
condensation of 4 (5)-imidazole carboxaldehyde, 4-(1 H-imidazole-1-yl) benzaldehyde and …

A structural chemistry perspective on the antimalarial properties of thiosemicarbazone metal complexes

KL Summers - Mini Reviews in Medicinal Chemistry, 2019 - ingentaconnect.com
Malaria is a potentially life-threatening disease, affecting approx. 214 million people
worldwide. Malaria is caused by a protozoan, Plasmodium falciparum, which is transmitted …

Optimized synthesis of new thiosemicarbazide derivatives with tuberculostatic activity

C Popovici, CM Pavel, V Sunel, C Cheptea… - International Journal of …, 2021 - mdpi.com
Original results are presented in the field of research that addresses the extension of the
reaction of residue of acyl-thiosemicarbazide fixation on the structure of 5 …

Phenoxyacetohydrazide Schiff Bases: β-Glucuronidase Inhibitors

W Jamil, S Perveen, SAA Shah, M Taha, NH Ismail… - Molecules, 2014 - mdpi.com
Phenoxyacetohydrazide Schiff base analogs 1–28 have been synthesized and their in vitro
β-glucouoronidase inhibition potential studied. Compounds 1 (IC50= 9.20±0.32 µM), 5 …

Synthesis, spectroscopic, and antimicrobial studies on bivalent nickel and copper complexes of bis (thiosemicrbazone)

S Chandra, S Raizada, M Tyagi… - Bioinorganic Chemistry …, 2007 - Wiley Online Library
A series of metal complexes of Cu (II) and Ni (II) having the general composition [M (L) X2]
with benzil bis (thiosemicarbazone) has been prepared and characterized by element …