The search for noise-induced cochlear synaptopathy in humans: Mission impossible?
N Bramhall, EF Beach, B Epp, CG Le Prell… - Hearing research, 2019 - Elsevier
Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …
Pathophysiology of subjective tinnitus: triggers and maintenance
Tinnitus is the conscious perception of a sound without a corresponding external acoustic
stimulus, usually described as a phantom perception. One of the major challenges for …
stimulus, usually described as a phantom perception. One of the major challenges for …
Evidence of cochlear neural degeneration in normal-hearing subjects with tinnitus
V Vasilkov, B Caswell-Midwinter, Y Zhao… - Scientific Reports, 2023 - nature.com
Tinnitus, reduced sound-level tolerance, and difficulties hearing in noisy environments are
the most common complaints associated with sensorineural hearing loss in adult …
the most common complaints associated with sensorineural hearing loss in adult …
The neural bases of tinnitus: lessons from deafness and cochlear implants
M Knipper, P Van Dijk, H Schulze… - Journal of …, 2020 - Soc Neuroscience
Subjective tinnitus is the conscious perception of sound in the absence of any acoustic
source. The literature suggests various tinnitus mechanisms, most of which invoke changes …
source. The literature suggests various tinnitus mechanisms, most of which invoke changes …
[HTML][HTML] Tinnitus with a normal audiogram: Relation to noise exposure but no evidence for cochlear synaptopathy
In rodents, exposure to high-level noise can destroy synapses between inner hair cells and
auditory nerve fibers, without causing hair cell loss or permanent threshold elevation. Such …
auditory nerve fibers, without causing hair cell loss or permanent threshold elevation. Such …
[HTML][HTML] Evidence of “hidden hearing loss” following noise exposures that produce robust TTS and ABR wave-I amplitude reductions
E Lobarinas, C Spankovich, CG Le Prell - Hearing research, 2017 - Elsevier
In animals, noise exposures that produce robust temporary threshold shifts (TTS) can
produce immediate damage to afferent synapses and long-term degeneration of low …
produce immediate damage to afferent synapses and long-term degeneration of low …
Weak middle-ear-muscle reflex in humans with noise-induced tinnitus and normal hearing may reflect cochlear synaptopathy
Chronic tinnitus is a prevalent hearing disorder, and yet no successful treatments or
objective diagnostic tests are currently available. The aim of this study was to investigate the …
objective diagnostic tests are currently available. The aim of this study was to investigate the …
The impact of tinnitus distress on cognition
Tinnitus is the chronic perception of a phantom sound with different levels of related distress.
Past research has elucidated interactions of tinnitus distress with audiological, affective and …
Past research has elucidated interactions of tinnitus distress with audiological, affective and …
Alterations in auditory brain stem response distinguish occasional and constant tinnitus
BACKGROUND The heterogeneity of tinnitus is thought to underlie the lack of objective
diagnostic measures. METHODS Longitudinal data from 20,349 participants of the Swedish …
diagnostic measures. METHODS Longitudinal data from 20,349 participants of the Swedish …
Auditory brainstem responses in tinnitus: a review of who, how, and what?
The auditory brainstem response (ABR) in tinnitus subjects has been extensively
investigated over the last decade with the hopes of finding possible abnormalities related to …
investigated over the last decade with the hopes of finding possible abnormalities related to …