Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development

N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …

Vaccine adjuvants revisited

JC Aguilar, EG Rodriguez - Vaccine, 2007 - Elsevier
The development of new adjuvants for human vaccines has become an expanding field of
research in the last thirty years, for generating stronger vaccines capable of inducing …

Virus-like particle vaccine induces protective immunity against homologous and heterologous strains of influenza virus

FS Quan, C Huang, RW Compans, SM Kang - Journal of virology, 2007 - Am Soc Microbiol
Recurrent outbreaks of highly pathogenic avian influenza virus pose the threat of pandemic
spread of lethal disease and make it a priority to develop safe and effective vaccines …

Different applications of virus‐like particles in biology and medicine: vaccination and delivery systems

Z Shirbaghaee, A Bolhassani - Biopolymers, 2016 - Wiley Online Library
Virus‐like particles (VLPs) mimic the whole construct of virus particles devoid of viral
genome as used in subunit vaccine design. VLPs can elicit efficient protective immunity as …

Recombinant vaccines in 2022: a perspective from the cell factory

MT de Pinho Favaro, J Atienza-Garriga… - Microbial cell …, 2022 - Springer
The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …

Virus-like particles: the new frontier of vaccines for animal viral infections

E Crisci, J Bárcena, M Montoya - Veterinary immunology and …, 2012 - Elsevier
Vaccination continues to be the main approach to protect animals from infectious diseases.
Until recently, all licensed vaccines were developed using conventional technologies …

Development of virus-like particle technology from small highly symmetric to large complex virus-like particle structures

P Pushko, P Pumpens, E Grens - Intervirology, 2013 - karger.com
Virus-like particle (VLP) technology is a promising approach for the construction of novel
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …

[HTML][HTML] Vaccine adjuvants–current status and prospects on controlled release adjuvancity

SM Sivakumar, MM Safhi, M Kannadasan… - Saudi Pharmaceutical …, 2011 - Elsevier
The strategy of World Health Organization is to develop efficient and inexpensive vaccine
against various infectious diseases amongst children's population. Vaccination is …

Virus‑like particles as a vaccine delivery system: Myths and facts

P Roy, R Noad - Human vaccines, 2008 - Taylor & Francis
Vaccines against viral disease have traditionally relied on attenuated virus strains or
inactivation of infectious virus. Subunit vaccines based on viral proteins expressed in …

New vaccines against influenza virus

YT Lee, KH Kim, EJ Ko, YN Lee… - Clinical and …, 2014 - synapse.koreamed.org
Vaccination is one of the most effective and cost-benefit interventions that prevent the
mortality and reduce morbidity from infectious pathogens. However, the licensed influenza …