Application of zebrafish in the study of the gut microbiome

X Zhong, J Li, F Lu, J Zhang… - Animal Models and …, 2022 - Wiley Online Library
Zebrafish (Danio rerio) have attracted much attention over the past decade as a reliable
model for gut microbiome research. Owing to their low cost, strong genetic and development …

Larval zebrafish as a model for mechanistic discovery in mental health

JXM Tan, RJW Ang, CL Wee - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Animal models are essential for the discovery of mechanisms and treatments for
neuropsychiatric disorders. However, complex mental health disorders such as depression …

The zebrafish gut microbiome influences benzo [a] pyrene developmental neurobehavioral toxicity

K Stagaman, A Alexiev, MJ Sieler, A Hammer… - Scientific Reports, 2024 - nature.com
Early-life exposure to environmental toxicants like Benzo [a] pyrene (BaP) is associated with
several health consequences in vertebrates (ie, impaired or altered neurophysiological and …

Cefotaxime Exposure-Caused Oxidative Stress, Intestinal Damage and Gut Microbial Disruption in Artemia sinica

H Pang, K Zheng, W Wang, M Zheng, Y Liu, H Yin… - Microorganisms, 2024 - mdpi.com
Cefotaxime (CTX) is an easily detectable antibiotic pollutant in the water environment, but
little is known about its toxic effects on aquatic invertebrates, especially on the intestine …

Defining the environmental determinants of dysbiosis at scale with zebrafish

TJ Sharpton, A Alexiev, RL Tanguay - Current opinion in toxicology, 2023 - Elsevier
The gut microbiome, critical to maintaining vertebrate homeostasis, is susceptible to various
exposures. In some cases, these exposures induce dysbiosis, wherein the microbiome …

Distinct members of the Caenorhabditis elegans CeMbio reference microbiota exert cryptic virulence that is masked by host defense

X Gonzalez, JE Irazoqui - Molecular Microbiology, 2024 - Wiley Online Library
Microbiotas are complex microbial communities that colonize specific niches in the host and
provide essential organismal functions that are important in health and disease …

Transplantation of high fat fed mouse microbiota into zebrafish larvae identifies MyD88‐dependent acceleration of hyperlipidaemia by Gram‐positive cell wall …

P Manuneedhi Cholan, S Morris, K Luo, J Chen… - …, 2022 - Wiley Online Library
Gut dysbiosis is an important modifier of pathologies including cardiovascular disease but
our understanding of the role of individual microbes is limited. Here, we have used …

[HTML][HTML] Distinct members of the C. elegans CeMbio reference microbiota exert cryptic virulence and infection protection

X Gonzalez, JE Irazoqui - bioRxiv, 2023 - ncbi.nlm.nih.gov
Microbiotas are complex microbial communities that colonize specific niches in the host and
provide essential organismal functions that are important in health and disease. A key …

Anti-diarrheal drug loperamide induces dysbiosis in zebrafish microbiota via bacterial inhibition

RJ Stevick, B Audrain, S Bedu, N Dray, JM Ghigo… - Microbiome, 2023 - Springer
Background Perturbations of animal-associated microbiomes from chemical stress can affect
host physiology and health. While dysbiosis induced by antibiotic treatments and disease is …

The zebrafish gut microbiome influences benzo [a] pyrene developmental neurotoxicity

K Stagaman, A Alexiev, M Sieler, A Hammer… - 2024 - researchsquare.com
Early-life exposure to environmental toxicants like Benzo [a] pyrene (BaP) is associated with
several health consequences in vertebrates (ie, impaired or altered neurophysiological and …