Peptide display technologies are a powerful method for discovery of new bioactive
sequences, but linear sequences are often very unstable in a biological setting …

Abstract Background Corona Virus Disease 2019 (COVID-19) is a global pandemic novel
coronavirus infection disease caused by Severe acute respiratory syndrome Coronavirus 2 …

The development of effective antiviral compounds is essential for mitigating the effects of the
COVID-19 pandemic. Entry of SARS-CoV-2 virions into host cells is mediated by the …

Abstract Purpose of Review This review aims to elucidate the mechanisms employed by
antiviral peptides in inhibiting coronaviruses as well as related limitations their therapeutic …

The use of viral protein inhibitors has shown to be insufficiently effective in the case of highly
variable SARS-CoV-2. In this work, we examined the possibility of designing agents that …

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel coronavirus,
is the causative agent responsible for the spread of the COVID19 pandemic across the …

To combat with emerging SARS-CoV-2 variants of concern (VOCs), we report the
identification of a set of unique HWK-motif peptide ligands for the receptor-binding domain …

The human complement pathway plays a pivotal role in immune defence, homeostasis, and
autoimmunity regulation, and complement-based therapeutics have emerged as promising …

We developed and validated a technology platform for designing and testing peptides
inhibiting the infectivity of SARS-CoV-2 spike protein-based pseudoviruses. This platform …

Genetically encoded peptide libraries are at the forefront of de novo drug discovery. The
RaPID (Random Nonstandard Peptides Integrated Discovery) platform stands out due to the …