A growing body of epidemiologic and experimental data point to chronic bacterial and viral
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …

Parkinson's disease (PD) is a common neurodegenerative disorder. Neuronal cell death in
PD is still poorly understood, despite a wealth of potential pathogenic mechanisms and …

BACKGROUND & AIMS: The Helicobacter pylori toxin vacuolating cytotoxin (VacA)
promotes gastric colonization, and its presence (VacA+) is associated with more-severe …

Different types of NPs (nanoparticles) are currently under development for diagnostic and
therapeutic applications in the biomedical field, yet our knowledge about their possible …

Aims This study evaluated SARS-CoV-2 replication in human cell lines derived from various
tissues and investigated molecular mechanisms related to viral infection susceptibility and …

Bacterial infection commonly complicates inflammatory airway diseases such as chronic
obstructive pulmonary disease (COPD). The mechanisms of increased infection …

Whether obesity accelerates or suppresses autophagy in adipose tissue is still debatable.
To clarify dysregulation of autophagy and its role in pathologies of obese adipose tissue, we …

BACKGROUND & AIMS: Acute pancreatitis is characterized by an activation cascade of
digestive enzymes in the pancreas. The first of these, trypsinogen, can be converted to …

Experimental and clinical therapies in the field of Alzheimer's disease (AD) have focused on
elimination of extracellular amyloid beta aggregates or prevention of cytoplasmic neuronal …

Abstract Treatment of MCF-7 cells with tamoxifen induced vacuole formation and cell death.
Levels of the autophagy marker, microtubule-associated protein light chain 3 (LC3)-II also …