The neuromuscular junction in health and disease: molecular mechanisms governing synaptic formation and homeostasis
PM Rodríguez Cruz, J Cossins, D Beeson… - Frontiers in molecular …, 2020 - frontiersin.org
The neuromuscular junction (NMJ) is a highly specialized synapse between a motor neuron
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …
Autoantibody specificities in myasthenia gravis; implications for improved diagnostics and therapeutics
K Lazaridis, SJ Tzartos - Frontiers in immunology, 2020 - frontiersin.org
Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness and
fatiguability of skeletal muscles. It is an antibody-mediated disease, caused by …
fatiguability of skeletal muscles. It is an antibody-mediated disease, caused by …
Myasthenia gravis—autoantibody characteristics and their implications for therapy
NE Gilhus, GO Skeie, F Romi, K Lazaridis… - Nature reviews …, 2016 - nature.com
Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies that target the
neuromuscular junction, leading to muscle weakness and fatigability. Currently available …
neuromuscular junction, leading to muscle weakness and fatigability. Currently available …
Seronegative autoimmune diseases: A challenging diagnosis
Autoimmune diseases (AID) are increasingly prevalent conditions which comprise more
than 100 distinct clinical entities that are responsible for a great disease burden worldwide …
than 100 distinct clinical entities that are responsible for a great disease burden worldwide …
Generalized myasthenia gravis: classification, clinical presentation, natural history, and epidemiology
MK Hehir, NJ Silvestri - Neurologic clinics, 2018 - neurologic.theclinics.com
Myasthenia gravis (MG) is the most common disorder of the neuromuscular junction. It is the
prototypic autoimmune disease most commonly caused by antibodies to the acetylcholine …
prototypic autoimmune disease most commonly caused by antibodies to the acetylcholine …
Myasthenia gravis: pathogenic effects of autoantibodies on neuromuscular architecture
I Koneczny, R Herbst - Cells, 2019 - mdpi.com
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction (NMJ).
Autoantibodies target key molecules at the NMJ, such as the nicotinic acetylcholine receptor …
Autoantibodies target key molecules at the NMJ, such as the nicotinic acetylcholine receptor …
Epidemiology, diagnostics, and biomarkers of autoimmune neuromuscular junction disorders
AR Punga, P Maddison, JM Heckmann… - The Lancet …, 2022 - thelancet.com
Autoimmune neuromuscular junction disorders are rare. However, myasthenia gravis is
being increasingly recognised in people older than 50 years. In the past 5–10 years …
being increasingly recognised in people older than 50 years. In the past 5–10 years …
Myasthenia gravis: a clinical-immunological update
Myasthenia gravis (MG) is the archetypic disorder of both the neuromuscular junction and
autoantibody-mediated disease. In most patients, IgG1-dominant antibodies to acetylcholine …
autoantibody-mediated disease. In most patients, IgG1-dominant antibodies to acetylcholine …
Myasthenia gravis with antibodies to MuSK: an update
A Evoli, PE Alboini, V Damato, R Iorio… - Annals of the New …, 2018 - Wiley Online Library
Myasthenia gravis with antibodies to the muscle‐specific tyrosine kinase (MuSK+ MG) is a
rare disease with distinctive pathogenic mechanisms and clinical features. An acute onset …
rare disease with distinctive pathogenic mechanisms and clinical features. An acute onset …
Myasthenia gravis: autoantibody specificities and their role in MG management
K Lazaridis, SJ Tzartos - Frontiers in neurology, 2020 - frontiersin.org
Myasthenia gravis (MG) is the most common autoimmune disorder affecting the
neuromuscular junction, characterized by skeletal muscle weakness and fatigability. It is …
neuromuscular junction, characterized by skeletal muscle weakness and fatigability. It is …