DEAD box RNA helicase functions in cancer

FV Fuller-Pace - RNA biology, 2013 - Taylor & Francis
Members of the DEAD box family of RNA helicases are known to be involved in most cellular
processes that require manipulation of RNA structure and, in many cases, exhibit other …

The DEAD-box protein family of RNA helicases: sentinels for a myriad of cellular functions with emerging roles in tumorigenesis

MAM Ali - International Journal of Clinical Oncology, 2021 - Springer
DEAD-box RNA helicases comprise a family within helicase superfamily 2 and make up the
largest group of RNA helicases. They are a profoundly conserved family of RNA-binding …

[PDF][PDF] DEAD box RNA helicases: crucial regulators of gene expression and oncogenesis

M Sarkar, MK Ghosh - Front Biosci (Landmark Ed), 2016 - article.imrpress.com
225 1. ABSTRACT DEAD box RNA helicases: crucial regulators of gene expression and
oncogenesis Moumita Sarkar1, Mrinal K. Ghosh1 Page 1 225 [Frontiers in Bioscience, Landmark …

Perturbations of RNA helicases in cancer

F Robert, J Pelletier - Wiley Interdisciplinary Reviews: RNA, 2013 - Wiley Online Library
Helicases are implicated in most stages of the gene expression pathway, ranging from DNA
replication, RNA transcription, splicing, RNA transport, ribosome biogenesis, mRNA …

DDX1 is a prognostic biomarker and correlates with immune infiltrations in hepatocellular carcinoma

M Yuan, J Xu, S Cao, S Sun - BMC immunology, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the leading lethal malignant tumors worldwide.
DEAD-box (DDX) family helicases are implicated in numerous human cancers. However …

[HTML][HTML] Subsite-specific association of DEAD box RNA helicase DDX60 with the development and prognosis of oral squamous cell carcinoma

TY Fu, CN Wu, HC Sie, JT Cheng, YS Lin, HH Liou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The clinical significance and biological function of DEXD/H box helicase 60 (DDX60) in oral
cancer remains unknown. Herein, we evaluated the association of DDX60 expression with …

Low expression of DDX60 gene might associate with the radiosensitivity for patients with breast cancer

D Xin, J Liu, J Gu, Y Ji, J Jin, L Sun, Q Tai… - Journal of …, 2020 - Wiley Online Library
DEXD/H box helicase 60 (DDX60) is a new type of DEAD‐box RNA helicase, which is
induced to express after virus infection. It might involve in antiviral immunity by promoting …

Epigenetic down-regulated DDX10 promotes cell proliferation through Akt/NF-κB pathway in ovarian cancer

M Gai, Q Bo, L Qi - Biochemical and biophysical research communications, 2016 - Elsevier
Ovarian cancer contributes to the majority of ovarian cancer, while the molecular
mechanisms remain elusive. Recently, some DEAD box protein 1 has been reported play a …

Oncodrive-CIS: a method to reveal likely driver genes based on the impact of their copy number changes on expression

D Tamborero, N Lopez-Bigas, A Gonzalez-Perez - PLoS One, 2013 - journals.plos.org
A well-established approach for detecting genes involved in tumorigenesis due to copy
number alterations (CNAs) is to assess the recurrence of the alteration across multiple …

[HTML][HTML] Germ lineage properties in the urochordate Botryllus schlosseri–from markers to temporal niches

A Rosner, E Moiseeva, C Rabinowitz… - Developmental Biology, 2013 - Elsevier
The primordial germ cells (PGCs) in the colonial urochordate Botryllus schlosseri are
sequestered in late embryonic stage. PGC-like populations, located at any blastogenic stage …