Typhaneoside-tetrahedral framework nucleic acids system: mitochondrial recovery and antioxidation for acute kidney injury treatment

R Yan, W Cui, W Ma, J Li, Z Liu, Y Lin - ACS nano, 2023 - ACS Publications
Acute kidney injury (AKI) is not only a worldwide problem with a cruel hospital mortality rate
but also an independent risk factor for chronic kidney disease and a promoting factor for its …

The Physics of micro-and nano-manipulation: Fundamentals and applications

S Zhuang, X Lin, X Yu, Z Zhao, F Liu, S Boccaletti… - Physics Reports, 2024 - Elsevier
Since the emergent advent of miniaturized technologies in the last century, the past ninety
years have witnessed the extensive use of micro-and nano-manipulation methods, which …

Suppression of lipopolysaccharide‐induced sepsis by tetrahedral framework nucleic acid loaded with quercetin

Z Liu, X Chen, W Ma, Y Gao, Y Yao, J Li… - Advanced Functional …, 2022 - Wiley Online Library
Sepsis has affected millions of people worldwide with high mortality rate and lack of effective
strategies. Previous studies have reported that quercetin (Que) can attenuate …

A polymeric approach toward resistance-resistant antimicrobial agent with dual-selective mechanisms of action

S Bai, J Wang, K Yang, C Zhou, Y Xu, J Song, Y Gu… - Science …, 2021 - science.org
Antibiotic resistance is now a major threat to human health, and one approach to combating
this threat is to develop resistance-resistant antibiotics. Synthetic antimicrobial polymers are …

Extracting physical chemistry from mechanics: a new approach to investigate DNA interactions with drugs and proteins in single molecule experiments

MS Rocha - Integrative Biology, 2015 - academic.oup.com
In this review we focus on the idea of establishing connections between the mechanical
properties of DNA–ligand complexes and the physical chemistry of DNA–ligand interactions …

Cellular microRNA detection with miRacles: microRNA-activated conditional looping of engineered switches

AR Chandrasekaran, M MacIsaac, P Dey… - Science …, 2019 - science.org
MicroRNAs are short noncoding regulatory RNAs that are increasingly used as disease
biomarkers. Detection of microRNAs can be arduous and expensive and often requires …

Ligand–Receptor Interaction-Induced Intracellular Phase Separation: A Global Disruption Strategy for Resistance-Free Lethality of Pathogenic Bacteria

A Yang, J Song, J Li, Y Li, S Bai, C Zhou… - Journal of the …, 2024 - ACS Publications
Addressing the global challenge of bacterial resistance demands innovative approaches,
among which multitargeting is a widely used strategy. Current strategies of multitargeting …

DNA‐doxorubicin interaction: New insights and peculiarities

EF Silva, RF Bazoni, EB Ramos, MS Rocha - Biopolymers, 2017 - Wiley Online Library
We have investigated the interaction of the DNA molecule with the anticancer drug
doxorubicin (doxo) by using three different experimental techniques: single molecule …

Cryopreservation and post-thaw characterization of dissociated human islet cells

LA Marquez-Curtis, XQ Dai, Y Hang, JY Lam, J Lyon… - PLoS …, 2022 - journals.plos.org
The objective of this study is to optimize the cryopreservation of dissociated islet cells and
obtain functional cells that can be used in single-cell transcriptome studies on the pathology …

Identification of novel nuclear factor of activated T cell (NFAT)-associated proteins in T cells

CH Gabriel, F Gross, M Karl, H Stephanowitz… - Journal of Biological …, 2016 - ASBMB
Transcription factors of the nuclear factor of activated T cell (NFAT) family are essential for
antigen-specific T cell activation and differentiation. Their cooperative DNA binding with …