Abstract Purpose of Review Juvenile-onset systemic lupus erythematosus ((j) SLE) is an
autoimmune/inflammatory disease that results in significant damage and disability. When …

Juvenile-onset systemic lupus erythematosus (jSLE) accounts for up to 20% of all SLE
patients. Key differences between juvenile-and adult-onset (aSLE) disease include higher …

Objective To estimate the incidence and prevalence of systemic lupus erythematosus (SLE)
in a sociodemographically diverse southeastern Michigan source population of 2.4 million …

Environmental exposures and the development of systemic lupu... : Current Opinion in
Rheumatology Environmental exposures and the development of systemic lupus erythematosus …

Objectives Significant differences have been reported in disease phenotype and severity of
systemic lupus erythematosus (SLE) presenting in different age groups. Most indicate a …

Chronic inflammatory arthritis in childhood is heterogeneous in presentation and course.
Most forms exhibit clinical and genetic similarity to arthritis of adult onset, although at least …

Systemic lupus erythematosus (SLE) is a clinically and genetically heterogeneous
autoimmune disease. The etiology of lupus and the contribution of genetic, environmental …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology
that primarily affects women of childbearing age. The development of SLE is attributed to the …

Monogenic lupus is a form of systemic lupus erythematosus (SLE) that occurs in patients
with a single gene defect. This rare variant of lupus generally presents with early onset …

There is growing evidence that preceding the diagnosis or classification of systemic lupus
erythematosus (SLE), patients undergo a preclinical phase of disease where markers of …