Data are accumulating that emphasize the important role of the intestinal barrier and
intestinal permeability for health and disease. However, these terms are poorly defined, their …

The human gut is colonized by a community of microbiota, primarily bacteria, that exist in a
symbiotic relationship with the host. Intestinal microbiota-host interactions play a critical role …

The gut mucosa acts as a barrier against microbial invaders, whereas resident commensal
and foreign invading bacteria interact intimately with the gut epithelium and influence the …

The human pathogens enteropathogenic and enterohemorrhagic Escherichia coli (EPEC
and EHEC) share a unique mechanism of colonization that results from the concerted action …

Microbial pathogens possess a diversity of weapons that disrupt host homeostasis and
immune defenses, thus resulting in the establishment of infection. The best-characterized …

The intestinal epithelial cell lining provides the first line of defense, yet foodborne pathogens
such as Listeria monocytogenes can overcome this barrier; however, the underlying …

The gastrointestinal epithelium deploys multiple innate defense mechanisms to fight
microbial intruders, including epithelial integrity, rapid epithelial cell turnover, quick …

Gastrointestinal disorders, although clinically heterogeneous, share pathogenic
mechanisms, including genetic susceptibility, impaired gut barrier function, altered …

Vibrio parahaemolyticus is a leading cause of seafood-borne gastroenteritis in many parts of
the world, but there is limited knowledge of the pathogenesis of V. parahaemolyticus …

Intestinal pathogenic Escherichia coli are a major cause of worldwide morbidity and
mortality. Currently seven intestinal pathovars are recognized causing a wide range of …