BP180 is critical in the autoimmunity of bullous pemphigoid

Y Liu, L Li, Y Xia - Frontiers in immunology, 2017 - frontiersin.org
Bullous pemphigoid (BP) is by far the most common autoimmune blistering dermatosis that
mainly occurs in the elderly. The BP180 is a transmembrane glycoprotein, which is highly …

Comorbidities and treatment strategies in bullous pemphigoid: an appraisal of the existing litterature

R Bech, L Kibsgaard, C Vestergaard - Frontiers in medicine, 2018 - frontiersin.org
Bullous Pemphigoid is an autoimmune skin blistering disease. It is caused by deposition of
auto antibodies along the dermal-epidermal border leading to inflammation. The antibodies …

Diverse targets of SMN2-directed splicing-modulating small molecule therapeutics for spinal muscular atrophy

EW Ottesen, NN Singh, D Luo, B Kaas… - Nucleic Acids …, 2023 - academic.oup.com
Designing an RNA-interacting molecule that displays high therapeutic efficacy while
retaining specificity within a broad concentration range remains a challenging task …

Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival

MC Beker, B Caglayan, AB Caglayan, T Kelestemur… - Scientific reports, 2019 - nature.com
The circadian rhythm is driven by a master clock within the suprachiasmatic nucleus which
regulates the rhythmic secretion of melatonin. Bmal1 coordinates the rhythmic expression of …

Consensus on the treatment of autoimmune bullous dermatoses: bullous pemphigoid, mucous membrane pemphigoid and epidermolysis bullosa acquisita-Brazilian …

CG Santi, AC Gripp, AM Roselino, DS Mello… - Anais brasileiros de …, 2019 - SciELO Brasil
Bullous pemphigoid, mucous membrane pemphigoid and epidermolysis bullosa acquisita
are subepidermal autoimmune blistering diseases whose antigenic target is located at the …

The laboratory domestication of zebrafish: from diverse populations to inbred substrains

J Suurväli, AR Whiteley, Y Zheng… - Molecular Biology …, 2020 - academic.oup.com
We know from human genetic studies that practically all aspects of biology are strongly
influenced by the genetic background, as reflected in the advent of “personalized medicine.” …

[HTML][HTML] Autoantibodies to BPAG1e trigger experimental bullous pemphigoid in mice

E Makita, Y Matsuzaki, T Fukui, A Matsui… - Journal of Investigative …, 2021 - Elsevier
Bullous pemphigoid (BP) is an autoimmune blistering disease that targets the
hemidesmosomal proteins BP180 and BP230/BPAG1e. Whereas the role of anti-BP180 …

Association between bullous pemphigoid and psychiatric disorders: A systematic review and meta‐analysis

IH Huang, PC Wu, CW Liu… - JDDG: Journal der …, 2022 - Wiley Online Library
Summary Background and Objectives Despite the well‐established association between
bullous pemphigoid (BP) and neurological diseases, the association between BP and …

Prognostic factors for mortality in bullous pemphigoid: A systematic review and meta-analysis

X Chen, Y Zhang, Z Luo, Y Wu, T Niu, J Zheng, Y Xie - Plos one, 2022 - journals.plos.org
Objective To systematically evaluate the prognostic factors for mortality in bullous
pemphigoid. Methods PubMed, Embase, Cochrane Library, China National Knowledge …

Mammalian plakins, giant cytolinkers: versatile biological functions and roles in cancer

L Hu, Z Huang, Z Wu, A Ali, A Qian - International Journal of Molecular …, 2018 - mdpi.com
Cancer is a highly lethal disease that is characterized by aberrant cell proliferation,
migration, and adhesion, which are closely related to the dynamic changes of cytoskeletons …