The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50%
of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical …

Membrane adsorbers (MA) are emerging as alternative unit operations in high-value protein
separation due to their many benefits, including short residence times, low pressure drop …

The purpose of this work was to compare side by side the performance of packed bed and
membrane chromatography adsorption processes for protein purification. The comparison …

Monolithic columns are a special type of chromatography column, which can be used for the
purification of different biomolecules. They have become popular due to their high mass …

A thermoresponsive copolymer incorporating a quaternary amine group, poly (N-
isopropylacrylamide-co-3-acrylamidopropyl trimethylammonium chloride (APTAC)-co-tert …

Plants are advantageous as biopharmaceutical manufacturing platforms because they allow
the economical and scalable upstream production of proteins, including those requiring post …

Hemostasis is a complex process for the cessation of bleeding from an injured blood vessel,
involving the interplay of 12 coagulation factors in the coagulation cascade with activated …

In this study we compare a nanofiber device and a resin column, both with the same Protein
A ligand, for the capture of four different monoclonal antibodies and a trivalent crystallizable …

The pressures to efficiently produce complex biopharmaceuticals at reduced costs are
driving the development of novel techniques, such as in downstream processing with …

Surface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization has
been utilized to fabricate high-capacity strong anion-exchange (AEX) membrane for the …