Protein analysis by shotgun/bottom-up proteomics
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
Common errors in mass spectrometry‐based analysis of post‐translational modifications
Mass spectrometry (MS) is a powerful tool to analyze complex mixtures of proteins in a high‐
throughput fashion. Proteome analysis has already become a routine task in biomedical …
throughput fashion. Proteome analysis has already become a routine task in biomedical …
Non-model organisms, a species endangered by proteogenomics
J Armengaud, J Trapp, O Pible, O Geffard… - Journal of …, 2014 - Elsevier
Previously, large-scale proteomics was possible only for organisms whose genomes were
sequenced, meaning the most common model organisms. The use of next-generation …
sequenced, meaning the most common model organisms. The use of next-generation …
Flexible and accessible workflows for improved proteogenomic analysis using the Galaxy framework
Proteogenomics combines large-scale genomic and transcriptomic data with mass-
spectrometry-based proteomic data to discover novel protein sequence variants and …
spectrometry-based proteomic data to discover novel protein sequence variants and …
[HTML][HTML] Annotation of the zebrafish genome through an integrated transcriptomic and proteomic analysis
DS Kelkar, E Provost, R Chaerkady… - Molecular & cellular …, 2014 - ASBMB
Accurate annotation of protein-coding genes is one of the primary tasks upon the completion
of whole genome sequencing of any organism. In this study, we used an integrated …
of whole genome sequencing of any organism. In this study, we used an integrated …
Immunity to visceral leishmaniasis: implications for immunotherapy
F Khadem, JE Uzonna - Future microbiology, 2014 - Taylor & Francis
Visceral leishmaniasis, caused by Leishmania donovani, L. infantum (syn. Leishmania
chagasi), is a globally widespread disease with a burden of about 400,000 new infections …
chagasi), is a globally widespread disease with a burden of about 400,000 new infections …
Understanding Leishmania parasites through proteomics and implications for the clinic
S Sundar, B Singh - Expert review of proteomics, 2018 - Taylor & Francis
Introduction: Leishmania spp. are causative agents of leishmaniasis, a broad-spectrum
neglected vector-borne disease. Genomic and transcriptional studies are not capable of …
neglected vector-borne disease. Genomic and transcriptional studies are not capable of …
[HTML][HTML] Identification of Differentially Expressed Proteins from Leishmania amazonensis Associated with the Loss of Virulence of the Parasites
RDM Magalhaes, MC Duarte, EC Mattos… - PLoS neglected …, 2014 - journals.plos.org
Background The present study analyzed whether or not the in vitro cultivation for long
periods of time of pre-isolated Leishmania amazonensis from lesions of chronically infected …
periods of time of pre-isolated Leishmania amazonensis from lesions of chronically infected …
Glycosomal targets for anti-trypanosomatid drug discovery
X Barros-Alvarez, M Gualdron-Lopez… - Current medicinal …, 2014 - ingentaconnect.com
Glycosomes are peroxisome-related organelles found in all kinetoplastid protists, including
the human pathogenic species of the family Trypanosomatidae: Trypanosoma brucei …
the human pathogenic species of the family Trypanosomatidae: Trypanosoma brucei …
Mass spectrometry in cancer biomarker research: a case for immunodepletion of abundant blood-derived proteins from clinical tissue specimens
DRA Prieto, DJ Johann Jr, BR Wei, X Ye… - Biomarkers in …, 2014 - Taylor & Francis
The discovery of clinically relevant cancer biomarkers using mass spectrometry (MS)-based
proteomics has proven difficult, primarily because of the enormous dynamic range of blood …
proteomics has proven difficult, primarily because of the enormous dynamic range of blood …