Synaptic plasticity abnormalities in fetal alcohol spectrum disorders

BS Basavarajappa, S Subbanna - Cells, 2023 - mdpi.com
The brain's ability to strengthen or weaken synaptic connections is often termed synaptic
plasticity. It has been shown to function in brain remodeling following different types of brain …

[HTML][HTML] Dysfunctions of cellular context-sensitivity in neurodevelopmental learning disabilities

A Granato, WA Phillips, JM Schulz, M Suzuki… - Neuroscience & …, 2024 - Elsevier
Pyramidal neurons have a pivotal role in the cognitive capabilities of neocortex. Though they
have been predominantly modeled as integrate-and-fire point processors, many of them …

Effects of developmental alcohol exposure on cortical multisensory integration

D Keum, K Pultorak, MA Meredith… - European Journal of …, 2023 - Wiley Online Library
Fetal alcohol spectrum disorder (FASD) is one of the most common causes of mental
disabilities in the world with a prevalence of 1%–6% of all births. Sensory processing deficits …

Optogenetic stimulation of corticostriatal circuits improves behavioral flexibility in mice with prenatal alcohol exposure

V Licheri, J Chandrasekaran, JA Kenton, CW Bird… - …, 2024 - Elsevier
Fetal alcohol spectrum disorder (FASD) is the most common preventable form of
developmental and neurobehavioral disability. Animal models have demonstrated that even …

Altering Cell-Cell Interaction in Prenatal Alcohol Exposure Models: Insight on Cell-Adhesion Molecules During Brain Development

V Licheri, JL Brigman - Frontiers in Molecular Neuroscience, 2021 - frontiersin.org
Alcohol exposure during pregnancy disrupts the development of the brain and produces
long lasting behavioral and cognitive impairments collectively known as Fetal Alcohol …

Sexually dimorphic organization of open field behavior following moderate prenatal alcohol exposure

JR Osterlund Oltmanns, EA Schaeffer… - Alcoholism: Clinical …, 2022 - Wiley Online Library
Background Prenatal alcohol exposure (PAE) can produce deficits in a wide range of
cognitive functions but is especially detrimental to behaviors requiring accurate spatial …

Maternal Alcohol Drinking Patterns Predict Offspring Neurobehavioral Outcomes

A Myrick, D Jimenez, B Jacquez, MS Sun, S Noor… - …, 2024 - Elsevier
The timing, rate, and quantity of gestational alcohol consumption, collectively referred to
here as Maternal Drinking Patterns (MDPs), are of known importance to fetal developmental …

Sex‐specific alterations in cognitive control following moderate prenatal alcohol exposure and transient systemic hypoxia ischemia in the rat

BR Dunn, SL Olguin, S Davies… - Alcohol: Clinical and …, 2024 - Wiley Online Library
Background Prenatal alcohol exposure (PAE) continues to be a worldwide problem. Affected
offspring display impaired neurodevelopment, including difficulties with executive control …

Long‐term effects of low prenatal alcohol exposure on GABAergic interneurons of the murine posterior parietal cortex

V Licheri, BJ Jacquez, VK Castillo… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background Fetal alcohol spectrum disorders (FASDs) are characterized by a wide range of
physical, cognitive, and behavioral impairments that occur throughout the lifespan. Prenatal …