MicroRNAs (miRNAs) are small noncoding RNAs that extensively regulate gene expression
in animals, plants, and protozoa. miRNAs function posttranscriptionally by usually base …

The RNA recognition motif (RRM), also known as RNA‐binding domain (RBD) or
ribonucleoprotein domain (RNP) is one of the most abundant protein domains in eukaryotes …

Transfer RNA-derived fragments (tRFs) are emerging small noncoding RNAs that, although
commonly altered in cancer, have poorly defined roles in tumorigenesis. Here we show that …

Most eukaryotic mRNAs are subject to considerable post-transcriptional modification,
including capping, splicing, and polyadenylation. The process of polyadenylation adds a …

MicroRNAs (miRNAs) posttranscriptionally regulate gene expression by repressing protein
synthesis and exert a broad influence over development, physiology, adaptation, and …

Poly (A) tails are found at the 3′ ends of almost all eukaryotic mRNAs. They are bound by
two different poly (A) binding proteins, PABPC in the cytoplasm and PABPN1 in the nucleus …

The binding of the eukaryotic initiation factor 4E (eIF4E) to the mRNA 5′ cap structure is a
rate-limiting step in mRNA translation initiation. eIF4E promotes ribosome recruitment to the …

La was first identified as a polypeptide component of ribonucleic protein complexes targeted
by antibodies in autoimmune patients and is now known to be a eukaryote cell‐ubiquitous …

Significant progress has been made over the past several years on structural studies of the
eukaryotic translation initiation factors that facilitate the assembly of a translation-competent …

Summry—Deregulation of gene expression is a hallmark of the cancer cell. Acquiring a new
profile of expressed proteins may enable the cell to re‐enter the cell cycle, or give them a …