Immunotherapy is one of the most promising clinical modalities for the treatment of
malignant tumors and has shown excellent therapeutic outcomes in clinical settings …

Immunotherapy has transformed the treatment landscape of many cancers, with durable
responses in disease previously associated with a poor prognosis. Patient selection remains …

The impressive development of cancer immunotherapy in the last few years originates from
a more precise understanding of control mechanisms in the immune system leading to the …

Tumor associated macrophages (TAM) are key players in the cancer microenvironment.
Molecular imaging modalities such as MRI and PET can be used to track and monitor TAM …

Poor healing ability and adhesion formation greatly hinder the recovery of injured tendon
function. Previously, our local sustained gene delivery system by using cyclooxygenases …

The adhesion family comprises one of the five major clades of G protein-coupled receptors
(GPCRs). Unlike conventional GPCRs, adhesion GPCRs (aGPCRs) have extended …

Tumor-associated macrophages (TAMs), the most abundant inflammatory cell group in the
tumor microenvironment, play an essential role in tumor immune regulation. The infiltration …

Highlights•Immunocytokines, a novel class of biopharmaceuticals against chronic
inflammation.•Disease-homing activity combined with immunomodulatory properties of …

Intermittent fasting (IF) and high-intensity interval training (HIIT) are procedures that might
mitigate the effects of nonalcoholic fatty liver disease. Two groups of 3-month-old C57BL/6 …

Cardiovascular diseases (CVDs) have been the leading cause of death in United States.
While tremendous progress has been made for treating CVDs over the year, the high …