Introduction 83% of those diagnosed with Parkinson's Disease (PD) eventually progress to
PD with mild cognitive impairment (PD-MCI) followed by dementia (PDD)-suggesting a …

Background and purpose The pathophysiology of Parkinson's disease (PD) negatively
affects brain network connectivity, and in the presence of brain white matter hyperintensities …

Type 2 diabetes mellitus (T2DM) and hypertension are risk factors for cerebral small vessel
disease (SVD); however, few studies have characterised their relationships with MRI-visible …

Background Cerebral small vessel disease is associated with higher ratios of soluble‐
epoxide hydrolase derived linoleic acid diols (12, 13‐dihydroxyoctadecenoic acid [DiHOME] …

INTRODUCTION We investigated whether novel plasma biomarkers are associated with
cognition, cognitive decline, and functional independence in activities of daily living across …

Background Neuropsychiatric symptoms (NPS) are a core feature of most
neurodegenerative and cerebrovascular diseases. White matter hyperintensities and brain …

The effective sharing of health research data within the healthcare ecosystem can have
tremendous impact on the advancement of disease understanding, prevention, treatment …

The tremendous increase in the use of video-based eye tracking has made it possible to
collect eye tracking data from thousands of participants. The traditional procedures for the …

Background Acute change in gait speed while performing a mental task [dual-task gait cost
(DTC)], and hyperintensity magnetic resonance imaging signals in white matter are both …

Background Symptoms of depression are present in neurodegenerative disorders (ND). It is
important that depression-related symptoms be adequately screened and monitored in …