[HTML][HTML] Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
H Slika, H Mansour, N Wehbe, SA Nasser… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …
Oxidative stress-induced endothelial dysfunction in cardiovascular diseases
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …
understanding of the mechanisms underlying CVD is key for better management or …
Nanozymes for regenerative medicine
X Mou, Q Wu, Z Zhang, Y Liu, J Zhang, C Zhang… - Small …, 2022 - Wiley Online Library
Nanozymes refer to nanomaterials that catalyze enzyme substrates into products under
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …
[HTML][HTML] Naturally occurring antioxidant therapy in Alzheimer's disease
AE Collins, TM Saleh, BE Kalisch - Antioxidants, 2022 - mdpi.com
It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …
2040. Although currently available treatments help with symptom management, they do not …
[HTML][HTML] Nrf2: An all-rounder in depression
C Zuo, H Cao, Y Song, Z Gu, Y Huang, Y Yang, J Miao… - Redox biology, 2022 - Elsevier
The balance between oxidation and antioxidant is crucial for maintaining homeostasis. Once
disrupted, it can lead to various pathological outcomes and diseases, such as depression …
disrupted, it can lead to various pathological outcomes and diseases, such as depression …
[HTML][HTML] Revisiting excitotoxicity in traumatic brain injury: from bench to bedside
D Baracaldo-Santamaría, DF Ariza-Salamanca… - Pharmaceutics, 2022 - mdpi.com
Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality.
Consequences vary from mild cognitive impairment to death and, no matter the severity of …
Consequences vary from mild cognitive impairment to death and, no matter the severity of …
[HTML][HTML] Traumatic brain injury: Mechanisms, manifestations, and visual sequelae
SH Rauchman, A Zubair, B Jacob… - Frontiers in …, 2023 - frontiersin.org
Traumatic brain injury (TBI) results when external physical forces impact the head with
sufficient intensity to cause damage to the brain. TBI can be mild, moderate, or severe and …
sufficient intensity to cause damage to the brain. TBI can be mild, moderate, or severe and …
[HTML][HTML] Maraviroc promotes recovery from traumatic brain injury in mice by suppression of neuroinflammation and activation of neurotoxic reactive astrocytes
XL Liu, DD Sun, MT Zheng, XT Li, HH Niu… - Neural regeneration …, 2023 - journals.lww.com
Neuroinflammation and the NACHT, LRR, and PYD domains-containing protein 3
inflammasome play crucial roles in secondary tissue damage following an initial insult in …
inflammasome play crucial roles in secondary tissue damage following an initial insult in …
Self‐propelled nanomotors with an alloyed engine for emergency rescue of traumatic brain injury
H Wang, X Chen, Y Qi, C Wang, L Huang… - Advanced …, 2022 - Wiley Online Library
In severe traumatic brain injury (sTBI), acute oxidative stress and inflammatory cascades
rapidly spread to cause irreversible brain damage and low survival rate within minutes …
rapidly spread to cause irreversible brain damage and low survival rate within minutes …
Kinases control of regulated cell death revealing druggable targets for Parkinson's disease
HM Mansour, AF Mohamed, AS El-Khatib… - Ageing Research …, 2023 - Elsevier
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder in the
world. Motor impairment seen in PD is associated with dopaminergic neurotoxicity in the …
world. Motor impairment seen in PD is associated with dopaminergic neurotoxicity in the …