Recent advances on signaling pathways and their inhibitors in rheumatoid arthritis

S Liu, H Ma, H Zhang, C Deng, P Xin - Clinical Immunology, 2021 - Elsevier
Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction
in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the …

The role of CDC25C in cell cycle regulation and clinical cancer therapy: a systematic review

K Liu, M Zheng, R Lu, J Du, Q Zhao, Z Li, Y Li… - Cancer Cell …, 2020 - Springer
One of the most prominent features of tumor cells is uncontrolled cell proliferation caused by
an abnormal cell cycle, and the abnormal expression of cell cycle-related proteins gives …

High-speed fluorescence image–enabled cell sorting

D Schraivogel, TM Kuhn, B Rauscher… - Science, 2022 - science.org
Fast and selective isolation of single cells with unique spatial and morphological traits
remains a technical challenge. Here, we address this by establishing high-speed image …

The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells

K Taketo, M Konno, A Asai… - International …, 2017 - spandidos-publications.com
N 6-methyladenosine (m6A) is the most abundant epitranscriptome modification in
mammalian mRNA. Recent years have seen substantial progress in m6A epitranscriptomics …

Neutrophil extracellular traps in breast cancer and beyond: current perspectives on NET stimuli, thrombosis and metastasis, and clinical utility for diagnosis and …

HT Snoderly, BA Boone, MF Bennewitz - Breast Cancer Research, 2019 - Springer
The formation of neutrophil extracellular traps (NETs), known as NETosis, was first observed
as a novel immune response to bacterial infection, but has since been found to occur …

Impact of lifestyles (diet and exercise) on vascular health: oxidative stress and endothelial function

AWC Man, H Li, N Xia - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2
diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between …

The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson's disease

A de Rus Jacquet, M Alpaugh, HL Denis… - Nature …, 2023 - nature.com
Astrocyte dysfunction has previously been linked to multiple neurodegenerative disorders
including Parkinson's disease (PD). Among their many roles, astrocytes are mediators of the …

The p38 MAPK components and modulators as biomarkers and molecular targets in cancer

L García-Hernández, MB García-Ortega… - International journal of …, 2021 - mdpi.com
The mitogen-activated protein kinase (MAPK) family is an important bridge in the
transduction of extracellular and intracellular signals in different responses at the cellular …

p53 and glucose metabolism: an orchestra to be directed in cancer therapy

AS Gomes, H Ramos, J Soares, L Saraiva - Pharmacological research, 2018 - Elsevier
Metabolic reprogramming is a hallmark of cancer with a strong impact on tumor cell survival,
proliferation, dissemination, and resistance to therapy. As such, it has represented a …

[HTML][HTML] Mesenchymal stem cell-associated lncRNA in osteogenic differentiation

C Ju, R Liu, YW Zhang, Y Zhang, R Zhou, J Sun… - Biomedicine & …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) have the ability to differentiate into multiple cell types,
including osteogenic, chondrogenic and adipogenic lineages. Osteogenic differentiation of …