Annotating protein sequences according to their biological functions is one of the key steps
in understanding microbial diversity, metabolic potentials, and evolutionary histories …

The equine gastrointestinal tract is a self-sufficient fermentation system, housing a complex
microbial consortium that acts synergistically and independently to break down complex …

Although gene-finding in bacterial genomes is relatively straightforward, the automated
assignment of gene function is still challenging, resulting in a vast quantity of hypothetical …

Elucidating the extracellular polymeric substances (EPS) of anammox granular sludge is
important for stable nitrogen removal processes in wastewater treatment. However, due to a …

Microorganisms represent the most abundant biomass on the planet; however, because of
several cultivation technique limitations, most of this genetic patrimony has been …

Background Hypothetical proteins [HP] are those that are predicted to be expressed in an
organism, but no evidence of their existence is known. In the recent past, annotation and …

The default removal of low-abundance (rare) taxa from microbial community analyses may
lead to an incomplete picture of the taxonomic and functional microbial potential within the …

Pseudomonas aeruginosa is an opportunistic gram-negative bacterium that has the
capability to acquire resistance under hostile conditions and become a threat worldwide. It is …

Background Genome-scale metabolic modeling is a cornerstone of systems biology analysis
of microbial organisms and communities, yet these genome-scale modeling efforts are …

Colorectal cancer (CRC) is one of the most common malignant tumors in the gastrointestinal
tract, and has been attracted a great deal attention and extensive investigation due to its …