Toxicology and pharmacology of synthetic organoselenium compounds: An update

CW Nogueira, NV Barbosa, JBT Rocha - Archives of Toxicology, 2021 - Springer
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

Organoselenium and organotellurium compounds: toxicology and pharmacology

CW Nogueira, G Zeni, JBT Rocha - Chemical reviews, 2004 - ACS Publications
Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds

CW Nogueira, JBT Rocha - Archives of Toxicology, 2011 - Springer
The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …

[HTML][HTML] Diphenyl diselenide a janus-faced molecule

CW Nogueira, JBT Rocha - Journal of the Brazilian Chemical Society, 2010 - SciELO Brasil
In this review, we summarized the potential role of synthetic organoseleno compounds as
therapeutic or toxic agents, giving emphasis almost exclusively to diphenyl diselenide, the …

A selanylimidazopyridine (3-SePh-IP) reverses the prodepressant-and anxiogenic-like effects of a high-fat/high-fructose diet in mice

IC Veloso, E Delanogare, AE Machado… - Journal of Pharmacy …, 2021 - academic.oup.com
Objective While chronic feeding with high-fat or high-sugar diets is known related to obesity
and type 2 diabetes, later data have indicated that it is also related to depression and …

Association of oxidative stress to the genesis of anxiety: implications for possible therapeutic interventions

W Hassan, C Eduardo Barroso Silva… - Current …, 2014 - ingentaconnect.com
Oxidative stress caused by reactive species, including reactive oxygen species, reactive
nitrogen species, and unbound, adventitious metal ions (eg, iron [Fe] and copper [Cu]), is an …

Diphenyl diselenide alleviates diabetic peripheral neuropathy in rats with streptozotocin-induced diabetes by modulating oxidative stress

X Wang, Y Huan, C Li, H Cao, S Sun, L Lei… - Biochemical …, 2020 - Elsevier
Diabetic peripheral neuropathy (DPN) is one of the most common microvascular
complications occurring in both type 1 and type 2 diabetes mellitus patients. Oxidative stress …

Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats

LP Borges, R Brandao, B Godoi, CW Nogueira… - Chemico-Biological …, 2008 - Elsevier
Cadmium is an environmental toxic metal implicated in human diseases. In the present
study, the effect of diphenyl diselenide,(PhSe) 2, on sub-chronic exposure with cadmium …

Diphenyl diselenide ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats via suppressing oxidative stress and inflammation

X Wang, C Li, Y Huan, H Cao, S Sun, L Lei… - Chemico-biological …, 2021 - Elsevier
Oxidative stress and inflammation are implicated in the occurrence and progression of
diabetic nephropathy (DN). Diphenyl diselenide (DPDS) is a stable and simple diaryl …

Brain and lungs of rats are differently affected by cigarette smoke exposure: antioxidant effect of an organoselenium compound

C Luchese, S Pinton, CW Nogueira - Pharmacological Research, 2009 - Elsevier
Cigarette smoke exposure has been associated with oxidative stress in several organs.
Antioxidant effect of diphenyl diselenide (PhSe) 2, an organoselenium compound, on …