There is evidence that excessive stress exposure of the brain, mediated through the
neurotoxic effects of cortisol and possibly neuroinflammation, causes damage to brain …

Accumulating evidence suggests that there is a rich cross-talk between the neuroimmune
system and neuroplasticity mechanisms under both physiological conditions and …

Objective The main purpose of this review was to synthesise evidence on ECT's effects on
brain's structure. Method A systematic literature review of longitudinal studies of depressed …

Background Major depressive disorder is a serious psychiatric illness with a highly variable
and heterogeneous clinical course. Due to the lack of consistent data from previous studies …

Background: Magnetic resonance imaging studies have provided evidence of structural
modifications in cortical-limbic regions in major depressive disorder. To date, however, few …

Leptin, produced and secreted by white adipose tissue, plays a critical role in regulating
body weight, food intake, and energy metabolism. Recently, several studies have identified …

Objective In a previous magnetic resonance imaging (MRI) study, we found a significant
increase in hippocampal volume immediately after electroconvulsive therapy (ECT) in …

Järnum H, Eskildsen SF, Steffensen EG, Lundbye‐Christensen S, Simonsen CW, Thomsen
IS, Fründ E‐T, Théberge J, Larsson E‐M. Longitudinal MRI study of cortical thickness …

Childhood adversity plays an important role for development of major depressive disorder
(MDD). There are differences in subcortical brain structures between patients with MDD and …

Background The hippocampal volume is reduced in patients with major depression.
Exercise leads to an increased hippocampal volume in schizophrenia and in healthy old …