Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm
The three main soil-transmitted helminth infections, ascariasis, trichuriasis, and hookworm,
are common clinical disorders in man. The gastrointestinal tract of a child living in poverty in …
are common clinical disorders in man. The gastrointestinal tract of a child living in poverty in …
[HTML][HTML] Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity
Helminths are masterful immunoregulators. A characteristic feature of helminth infection is a
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …
Hookworm infection
In areas of rural poverty in the tropics and subtropics, more than 700 million persons are
infected with the parasites Necator americanus and Ancylostoma duodenale. The adult …
infected with the parasites Necator americanus and Ancylostoma duodenale. The adult …
Immunomodulation by helminth parasites: defining mechanisms and mediators
Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …
models, strongly indicate that helminth parasitic infections can confer protection from …
The CAP superfamily: cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins—roles in reproduction, cancer, and immune defense
GM Gibbs, K Roelants, MK O'bryan - Endocrine reviews, 2008 - academic.oup.com
The cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins (CAP)
superfamily members are found in a remarkable range of organisms spanning each of the …
superfamily members are found in a remarkable range of organisms spanning each of the …
The sterol‐binding activity of PATHOGENESIS‐RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein
J Gamir, R Darwiche, P Van't Hof… - The Plant …, 2017 - Wiley Online Library
Pathogenesis‐related proteins played a pioneering role 50 years ago in the discovery of
plant innate immunity as a set of proteins that accumulated upon pathogen challenge. The …
plant innate immunity as a set of proteins that accumulated upon pathogen challenge. The …
The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus
Background The barber's pole worm, Haemonchus contortus, is one of the most
economically important parasites of small ruminants worldwide. Although this parasite can …
economically important parasites of small ruminants worldwide. Although this parasite can …
Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths
DJ Diemert, AG Pinto, J Freire, A Jariwala… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Necator americanus Ancylostoma-secreted protein 2 (Na-ASP-2) is
secreted by infective hookworm larvae on entry into human hosts. Vaccination of laboratory …
secreted by infective hookworm larvae on entry into human hosts. Vaccination of laboratory …
Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome
A subunit vaccine, RBD-S, is under development to prevent severe acute respiratory
syndrome (SARS) caused by SARS coronavirus (SARS-CoV), which is classified by the US …
syndrome (SARS) caused by SARS coronavirus (SARS-CoV), which is classified by the US …
Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) …
JP Hewitson, Y Harcus, J Murray, M van Agtmaal… - Journal of …, 2011 - Elsevier
The intestinal helminth parasite, Heligmosomoides polygyrus bakeri offers a tractable
experimental model for human hookworm infections such as Ancylostoma duodenale and …
experimental model for human hookworm infections such as Ancylostoma duodenale and …