Thrombocytopenia in chronic liver disease

M Peck‐Radosavljevic - Liver International, 2017 - Wiley Online Library
Thrombocytopenia is a common haematological disorder in patients with chronic liver
disease. It is multifactorial and severity of liver disease is the most influential factor. As a …

Management of varices and variceal hemorrhage in cirrhosis

G Garcia-Tsao, J Bosch - New England Journal of Medicine, 2010 - Mass Medical Soc
Gastroesophageal varices are present at diagnosis in almost half of patients with cirrhosis,
and variceal hemorrhage continues to be a lethal complication of cirrhosis. This review …

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update

CPG Panel, A Berzigotti, E Tsochatzis, J Boursier… - Journal of …, 2021 - Elsevier
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

GM Hirschfield, JK Dyson, GJM Alexander… - Gut, 2018 - gut.bmj.com
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …

Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: the “Anticipate” study

JG Abraldes, C Bureau, H Stefanescu, S Augustin… - Hepatology, 2016 - journals.lww.com
In patients with compensated advanced chronic liver disease (cACLD), the presence of
clinically significant portal hypertension (CSPH) and varices needing treatment (VNT) bears …

[HTML][HTML] EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis

European Association for the Study of the Liver - Journal of hepatology, 2015 - Elsevier
Liver fibrosis is part of the structural and functional alterations in most chronic liver diseases.
It is one of the main prognostic factors as the amount of fibrosis is correlated with the risk of …

Elastography, spleen size, and platelet count identify portal hypertension in patients with compensated cirrhosis

A Berzigotti, S Seijo, U Arena, JG Abraldes, F Vizzutti… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Noninvasive methods are needed to identify clinically significant
portal hypertension (CSPH) and esophageal varices (EVs) in patients with compensated …

Measurement of spleen stiffness to evaluate portal hypertension and the presence of esophageal varices in patients with HCV-related cirrhosis

A Colecchia, L Montrone, E Scaioli… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: The hepatic vein pressure gradient (HVPG) is the standard used to
determine the degree of portal hypertension (PH) and an important prognostic factor for …

Assessing portal hypertension in liver diseases

A Berzigotti, S Seijo, E Reverter… - Expert review of …, 2013 - Taylor & Francis
Portal hypertension is a common complication of chronic liver diseases and is responsible
for most clinical consequences of cirrhosis, which represent the more frequent causes of …

[HTML][HTML] Chronic hepatitis C and liver fibrosis

G Sebastiani, K Gkouvatsos… - World journal of …, 2014 - ncbi.nlm.nih.gov
Chronic infection with hepatitis C virus (HCV) is a leading cause of liver-related morbidity
and mortality worldwide and predisposes to liver fibrosis and end-stage liver complications …