Type A viral hepatitis: A summary and update on the molecular virology, epidemiology, pathogenesis and prevention

SM Lemon, JJ Ott, P Van Damme, D Shouval - Journal of Hepatology, 2018 - Elsevier
Although epidemic jaundice was well known to physicians of antiquity, it is only in recent
years that medical science has begun to unravel the origins of hepatitis A virus (HAV) and …

Viral quasispecies evolution

E Domingo, J Sheldon, C Perales - Microbiology and Molecular …, 2012 - Am Soc Microbiol
Evolution of RNA viruses occurs through disequilibria of collections of closely related mutant
spectra or mutant clouds termed viral quasispecies. Here we review the origin of the …

Tumor-derived exosomal HMGB1 fosters hepatocellular carcinoma immune evasion by promoting TIM-1+ regulatory B cell expansion

L Ye, Q Zhang, Y Cheng, X Chen, G Wang… - … for immunotherapy of …, 2018 - Springer
Abstract Background Regulatory B (Breg) cells represent one of the B cell subsets that
infiltrate solid tumors and exhibit distinct phenotypes in different tumor microenvironments …

[PDF][PDF] WHO immunological basis for immunization series: module 18: hepatitis A

World Health Organization - 2019 - apps.who.int
MAVS Mitochondrial antiviral signaling protein MMR Measles, mumps and rubella vaccine
MSM Men who have sex with men LAK Lymphokine-activated killer cells NK cells Natural …

Living in the liver: hepatic infections

U Protzer, MK Maini, PA Knolle - Nature Reviews Immunology, 2012 - nature.com
The liver has vital metabolic and clearance functions that involve the uptake of nutrients,
waste products and pathogens from the blood. In addition, its unique immunoregulatory …

Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury

T Ichimura, JV Bonventre, V Bailly, H Wei… - Journal of Biological …, 1998 - ASBMB
We report the identification of rat and human cDNAs for a type 1 membrane protein that
contains a novel six-cysteine immunoglobulin-like domain and a mucin domain; it is named …

The cell biology of receptor-mediated virus entry

J Grove, M Marsh - Journal of Cell Biology, 2011 - rupress.org
The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental
cellular processes to gain entry to cells and deliver their genetic cargo. Virus entry pathways …

[HTML][HTML] Understanding kidney injury molecule 1: a novel immune factor in kidney pathophysiology

J Song, J Yu, GW Prayogo, W Cao, Y Wu… - American journal of …, 2019 - ncbi.nlm.nih.gov
Abstract Kidney injury molecule 1 (KIM-1) is a type I membrane protein, comprising an
extracellular portion and a cytoplasmic portion. It is also named as HAVCR1 (Hepatitis A …

Viral apoptotic mimicry

A Amara, J Mercer - Nature Reviews Microbiology, 2015 - nature.com
As opportunistic pathogens, viruses have evolved many elegant strategies to manipulate
host cells for infectious entry and replication. Viral apoptotic mimicry, defined by the …

TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

GJ Freeman, JM Casasnovas, DT Umetsu… - Immunological …, 2010 - Wiley Online Library
The TIM (T cell/transmembrane, immunoglobulin, and mucin) gene family plays a critical role
in regulating immune responses, including allergy, asthma, transplant tolerance …