Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Lanthanide probes for bioresponsive imaging

MC Heffern, LM Matosziuk, TJ Meade - Chemical reviews, 2014 - ACS Publications
The chemistry of the less familiar elements is a fascinating topic especially for the inorganic
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …

Challenges for molecular magnetic resonance imaging

E Terreno, DD Castelli, A Viale, S Aime - Chemical reviews, 2010 - ACS Publications
Challenges for Molecular Magnetic Resonance Imaging | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most …

Inorganic and bioinorganic solvent exchange mechanisms

L Helm, AE Merbach - Chemical reviews, 2005 - ACS Publications
The simplest reaction on a metal ion in aqueous or nonaqueous solution is the exchange of
a solvent molecule between the first and second coordination shells (eq 1). This reaction is …

High‐relaxivity MRI contrast agents: where coordination chemistry meets medical imaging

EJ Werner, A Datta, CJ Jocher… - Angewandte Chemie …, 2008 - Wiley Online Library
The desire to improve and expand the scope of clinical magnetic resonance imaging (MRI)
has prompted the search for contrast agents of higher efficiency. The development of better …

Lanthanides in magnetic resonance imaging

M Bottrill, L Kwok, NJ Long - Chemical Society Reviews, 2006 - pubs.rsc.org
Magnetic Resonance Imaging is perhaps the most important and prominent technique in
diagnostic clinical medicine and biomedical research. Its success and development as an …

Gd (III)-based contrast agents for MRI

S Aime, M Botta, E Terreno - Adv. Inorg. Chem, 2005 - books.google.com
I. General remarks 173 II. Contribution to the relaxivity 176 A. Inner-sphere contribution to
the relaxivity 178 B. Outer-sphere contribution to the relaxivity 184 C. Second-sphere …

Fine-tuning the pH trigger of self-assembly

A Ghosh, M Haverick, K Stump, X Yang… - Journal of the …, 2012 - ACS Publications
The creation of smart, self-assembling materials that undergo morphological transitions in
response to specific physiological environments can allow for the enhanced accumulation of …

Environmentally responsive MRI contrast agents

GL Davies, I Kramberger, JJ Davis - Chemical Communications, 2013 - pubs.rsc.org
Biomedical imaging techniques can provide a vast amount of anatomical information,
enabling diagnosis and the monitoring of disease and treatment profile. MRI uniquely offers …

Squalene based nanocomposites: a new platform for the design of multifunctional pharmaceutical theragnostics

JL Arias, LH Reddy, M Othman, B Gillet, D Desmaele… - ACS …, 2011 - ACS Publications
This study reports the design of a novel theragnostic nanomedicine which combines (i) the
ability to target a prodrug of gemcitabine to an experimental solid tumor under the influence …