Background: Spirothiazolidines are versatile synthetic scaffold possessing wide spectrum of
biological interests involving potential anticancer activity. Objective: To report the first …

Heterocyclic compounds constitute a unique class of organic compounds endowed with a
wide range of synthetic and pharmaceutical applications. Pyrimidinones and their fused …

Hepatocellular carcinoma (HCC), also known as hepatoma, is the most prevalent type of
primary liver cancer. It begins in the hepatocytes, the liver's major cell type. Cancer that …

A series of novel pyridine and fused pyridine derivatives have been prepared starting from 6-
(3, 4-dimethylphenyl)-2-hydrazinyl-4-(thiophen-2-yl)-pyridine-3-carbonitrile 1 which on …

4-(4-Aminophenyl)-1-thia-4-azaspiro [4.5] decan-3-one 1 was prepared and allowed to react
with nitrogen nucleophiles to give the corresponding hydrazones 2–4. Further, compound 1 …

This study involved designing and synthesizing new derivatives of pyrazolo [1, 5-a]
pyrimidine 5a-l, which were prepared via reaction of 4-Arylazo-1H-pyrazole-3, 5-diamines …

Herein, a new series of spirothiazolidine derivatives 1–14 are effectively produced using
microwave irradiation in a quick and efficient manner. IR, NMR, and mass spectra were used …

Searching for a chemopreventive agent is an important approach for breast cancer
management. The aim of the study was to evaluate the chemopreventive potential of Ulmus …

Iminophosphoranes reacted with CS 2 at–5° C to produce the isothiocyanates, which were
treated with primary amine to give thioureas in 73–91% yields. The subsequent reaction of …

The usefulness of small ring heterocyclic compound has been clearly shown in recently
years [1-3]. Threemembered heterocycles are invested with a special allure that is derived …