Targeting the hedgehog (HH) pathway to treat aggressive cancers of the brain, breast,
pancreas, and prostate has been ongoing for decades. Gli gene amplifications have been …

Opinion statement Medulloblastoma (MB) is a malignant embryonal tumor of the posterior
fossa and is the most common type of brain cancer in pediatric patients. In contrast, adult MB …

Adult medulloblastoma is a rare tumor with few retrospective studies published so far. The
role of adjuvant chemotherapy or chemotherapy at relapse is unclear. This study reports …

Medulloblastoma is the most common central nervous system tumor in children, while it is
extremely rare in adults. Multimodal treatment involving surgery, radiotherapy and …

We retrospectively studied 26 consecutive adults treated for medulloblastoma using
paediatric protocols. Between 1987 and 2003, patients⩾ 18 years old were given adjuvant …

PURPOSE: Myeloablative regimens were frequently used for medulloblastoma relapsing
after craniospinal irradiation (CSI): in 1997–2002, we used repeated surgery, standard-dose …

We previously demonstrated that Busulfan–Thiotepa (Bu–Thio) and ASCT effectively treated
patients with locally relapsed medulloblastoma after surgery and conventional …

Purpose To evaluate the efficacy and toxicity of hypofractionated stereotactic radiotherapy in
the management of locally recurrent or residual central nervous system (CNS) primitive …

BACKGROUND Embryonal central nervous system (CNS) tumors (medulloblastoma,
cerebral neuroblastoma, pineoblastoma, and primitive neuroectodermal tumors) are rare in …

BACKGROUND Most medulloblastomas express high levels of somatostatin type 2
receptors (sst2). DOTA0‐D‐Phe1‐Tyr3‐octreotide (DOTATOC) specifically binds sst2 in the …