Applications in awake animal magnetic resonance imaging

CF Ferris - Frontiers in neuroscience, 2022 - frontiersin.org
There are numerous publications on methods and applications for awake functional MRI
across different species, eg, voles, rabbits, cats, dogs, and rhesus macaques. Each of these …

Where do we stand on fMRI in awake mice?

F Mandino, S Vujic, J Grandjean, EMR Lake - Cerebral cortex, 2024 - academic.oup.com
Imaging awake animals is quickly gaining traction in neuroscience as it offers a means to
eliminate the confounding effects of anesthesia, difficulties of inter-species translation (when …

Effects of inhaled cannabis high in Δ9-THC or CBD on the aging brain: A translational MRI and behavioral study

AH Sadaka, J Canuel, M Febo, CT Johnson… - Frontiers in Aging …, 2023 - frontiersin.org
With the recent legalization of inhaled cannabis for medicinal and recreational use, the
elderly represents one of the newest, rapidly growing cohorts of cannabis users. To …

Medial prefrontal cortex mechanisms of cannabidiol-induced aversive memory reconsolidation impairments

H Bayer, CAJ Stern, F Troyner, L Gazarini… - …, 2022 - Elsevier
Growing evidence indicates that cannabidiol (CBD), a substance present in the Cannabis
sativa plant, has potential therapeutic value to regulate abnormal emotional memories …

Cannabidiol treatment improves glucose metabolism and memory in streptozotocin-induced Alzheimer's disease rat model: a proof-of-concept study

D de Paula Faria, L Estessi de Souza… - International Journal of …, 2022 - mdpi.com
An early and persistent sign of Alzheimer's disease (AD) is glucose hypometabolism, which
can be evaluated by positron emission tomography (PET) with 18F-2-fluoro-2-deoxy-D …

Changes in brain structure and function following chronic exposure to inhaled vaporised cannabis during periadolescence in female and male mice: A multimodal MRI …

JR Coleman, D Madularu, RJ Ortiz… - Addiction …, 2022 - Wiley Online Library
Abstract Background and Aims Social norms and legality surrounding the use of medical
and recreational cannabis are changing rapidly. The prevalence of cannabis use in …

Developmental changes in brain structure and function following exposure to oral LSD during adolescence

L Harris-Blum, Z Smith, RJ Ortiz, D Athreya, A Chang… - Scientific reports, 2024 - nature.com
LSD is a hallucinogen with complex neurobiological and behavioral effects. Underlying
these effects are changes in brain neuroplasticity. This is the first study to follow the …

Effects of (−)‐MBP, a novel 5‐HT2C agonist and 5‐HT2A/2B antagonist/inverse agonist on brain activity: A phMRI study on awake mice

PK Sathe, GR Ramdasi, K Giammatteo… - Pharmacology …, 2023 - Wiley Online Library
Abstract A novel serotonin ligand (−)‐MBP was developed for the treatment of schizophrenia
that has 5‐HT2A/2B antagonist activity together with 5‐HT2C agonist activity. The multi …

Differences in Inhibitory Control and Resting Brain Metabolism between Older Chronic Users of Tetrahydrocannabinol (THC) or Cannabidiol (CBD)—A Pilot Study

T Rudroff, CD Workman, PE Gander, JR Deters… - Brain sciences, 2022 - mdpi.com
Δ9-Tetrahydrocannabinol is the main psychoactive component of cannabis and cannabidiol
is purportedly responsible for many of the medicinal benefits. The effects of Δ9 …

Dose-dependent LSD effects on cortical/thalamic and cerebellar activity: brain oxygen level–dependent fMRI study in awake rats

A Ghaw, A Chunduri, A Chang, RJ Ortiz… - Brain …, 2024 - academic.oup.com
Lysergic acid diethylamide is a hallucinogen with complex neurobiological and behavioural
effects. This is the first study to use MRI to follow functional changes in brain activity in …