Astrocytes, initially described as merely support cells, are now known as a heterogeneous
population of cells actively involved in a variety of biological functions such as: neuronal …

Thyroid hormones (TH) are essential for normal brain development. Even modest degrees of
TH disruption experienced in utero can result in neuropsychological deficits in children …

Thyroid hormone disorders have long been linked to depression, but the causal relationship
between them remains controversial. To address this question, we established rat models of …

Nongenomic effects of thyroid hormones typically start at the cell surface and do not
primarily involve the classical nuclear receptors, but rather a plasma membrane receptor site …

Thyroid hormones (TH) play crucial roles in brain maturation and are important for neuronal
migration and neocortical lamination. Subcortical band heterotopia (SBH) represent a class …

The effects of the well‑known peroxisome proliferator‑activated receptor gamma (PPAR-γ)
agonist rosiglitazone (Rosi) on brain‑derived neurotrophic factor (BDNF), nitric oxide (NO) …

Background and Purpose—Low level of thyroid hormone is a strong independent risk factor
for white matter (WM) injury, a major cause of cerebral palsy, in preterm infants. Thyroxin …

Brain-derived neurotrophic factor (BDNF) is a neurotrophin critical for many developmental
and physiological aspects of CNS function. Severe hypothyroidism in the early neonatal …

Introduction Thyroid hormones play an essential role in hippocampal development, a key
structure in psychosis. However, the role of these hormones in first-episode psychosis (FEP) …

Maternal subclinical hypothyroidism (SCH) during pregnancy can adversely affect the
neurodevelopment of the offspring. The balance of nerve growth factor (NGF)-related …