The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

So far, only two retroviruses, human immunodeficiency virus (HIV)(type 1 and 2) and human
T-cell lymphotropic virus type 1 (HTLV-1), have been recognized as pathogenic for humans …

Multiplexed imaging and spatial transcriptomics enable highly resolved spatial
characterization of cellular phenotypes, but still largely depend on laborious manual …

While the number of studies related to severe acute respiratory syndrome-related
coronavirus 2 (SARS-CoV-2) is constantly growing, it is essential to provide a framework of …

Abstract Three-dimensional (3D) human tissue models/microphysiological systems (eg,
organs-on-chips, organoids, and tissue explants) model HIV and related comorbidities and …

Simulations of tissue-specific effects of primary acute viral infections like COVID-19 are
essential for understanding disease outcomes and optimizing therapies. Such simulations …

Cytotoxic T cells are important components of natural anti-tumor immunity and are
harnessed in tumor immunotherapies. Immune responses to tumors and immune therapy …

Infectious diseases and cancer evade immune surveillance using similar mechanisms.
Targeting immune mechanisms using common strategies thus represents a promising …

Contributing to organ formation and tissue regeneration, extracellular matrix (ECM)
constituents provide tissue with three-dimensional (3D) structural integrity and cellular …

A critical step in the life cycle of a virus is spread to a new target cell, which generally
involves the release of new viral particles from the infected cell which can then initiate …