Myricetin inhibits TNF-α-induced inflammation in A549 cells via the SIRT1/NF-κB pathway

M Chen, Z Chen, D Huang, C Sun, J Xie, T Chen… - Pulmonary …, 2020 - Elsevier
Background Although myricetin exerts anti-inflammation, anti-cancer, and anti-oxidation
effects, the relationship between myricetin and tumor necrosis factor alpha (TNF-α) …

Current perspectives on the role of interleukin-1 signalling in the pathogenesis of asthma and COPD

ET Osei, CA Brandsma, W Timens… - European …, 2020 - Eur Respiratory Soc
Asthma and chronic obstructive pulmonary disease (COPD) cause significant morbidity and
mortality worldwide. In the context of disease pathogenesis, both asthma and COPD involve …

Molecular and cellular mechanisms responsible for beneficial effects of mesenchymal stem cell‐derived product “exo‐d‐MAPPS” in attenuation of chronic airway …

CR Harrell, D Miloradovic, R Sadikot… - Analytical Cellular …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs), due to their potential for differentiation into alveolar
epithelial cells and their immunosuppressive characteristics, are considered a new …

A hypoxia-driven occurrence of chronic kidney disease and osteoporosis in COPD individuals: New insights into environmental cadmium exposure

A Cirovic, A Denic, BL Clarke, R Vassallo, A Cirovic… - Toxicology, 2022 - Elsevier
Humans are exposed to cadmium via a variety of anthropogenic and natural pathways.
Hypoxia, a key pathophysiological consequence of chronic obstructive pulmonary disease …

Hydrogen sulfide inhibits cigarette smoke-induced inflammation and injury in alveolar epithelial cells by suppressing PHD2/HIF-1α/MAPK signaling pathway

R Guan, J Wang, D Li, Z Li, H Liu, M Ding, Z Cai… - International …, 2020 - Elsevier
Chronic obstructive pulmonary fibrosis (COPD) is a chronic and fatal lung disease with few
treatment options. Sodium hydrosulfide (NaHS), a donor of hydrogen sulfide (H 2 S), was …

[HTML][HTML] Shared mechanisms of multimorbidity in COPD, atherosclerosis and type-2 diabetes: the neutrophil as a potential inflammatory target

MJ Hughes, HM McGettrick… - European Respiratory …, 2020 - Eur Respiratory Soc
Multimorbidity is increasingly common and current healthcare strategies are not always
aligned to treat this complex burden of disease. COPD, type-2 diabetes mellitus (T2D) and …

[HTML][HTML] Chronic obstructive pulmonary disease and the development of atrial fibrillation

M Grymonprez, V Vakaet, M Kavousi… - International Journal of …, 2019 - Elsevier
Background Chronic obstructive pulmonary disease (COPD) has been associated with atrial
fibrillation (AF). More insight into the epidemiology and underlying mechanisms is required …

Change of serum inflammatory cytokines levels in patients with chronic obstructive pulmonary disease, pneumonia and lung cancer

J Chen, X Li, CL Huang, Y Lin… - Technology in Cancer …, 2020 - journals.sagepub.com
Objective: This study aimed to investigate the serum inflammatory cytokines levels in
patients with COPD, pneumonia and lung cancer, and assess the correlation between the …

Status of TNF-α and IL-6 as pro-inflammatory cytokines in exhaled breath condensate of late adolescents with asthma and healthy in the dust storm and non-dust …

MG Ghozikali, K Ansarin, K Naddafi… - Science of The Total …, 2022 - Elsevier
Exposure to airborne particulate matter (PM) can be considered as an important risk factor
for human health. Some cytokines have been recognized as the biomarkers of exposure to …

Th1/Th17 cytokine profiles are associated with disease severity and exacerbation frequency in COPD patients

Y Yu, L Zhao, Y Xie, Y Xu, W Jiao, J Wu… - … Journal of Chronic …, 2020 - Taylor & Francis
Background T helper (Th) cell cytokine imbalances have been associated with the
pathophysiology of chronic obstructive pulmonary disease (COPD), including the Th1/Th2 …