Molecular mechanisms of dietary restriction promoting health and longevity
CL Green, DW Lamming, L Fontana - Nature Reviews Molecular Cell …, 2022 - nature.com
Dietary restriction with adequate nutrition is the gold standard for delaying ageing and
extending healthspan and lifespan in diverse species, including rodents and non-human …
extending healthspan and lifespan in diverse species, including rodents and non-human …
Clinical application of intermittent fasting for weight loss: progress and future directions
KA Varady, S Cienfuegos, M Ezpeleta… - Nature Reviews …, 2022 - nature.com
Intermittent fasting diets have become very popular in the past few years, as they can
produce clinically significant weight loss. These diets can be defined, in the simplest of …
produce clinically significant weight loss. These diets can be defined, in the simplest of …
Effectiveness of early time-restricted eating for weight loss, fat loss, and cardiometabolic health in adults with obesity: a randomized clinical trial
Importance It is unclear how effective intermittent fasting is for losing weight and body fat,
and the effects may depend on the timing of the eating window. This randomized trial …
and the effects may depend on the timing of the eating window. This randomized trial …
[HTML][HTML] Effects of 4-and 6-h time-restricted feeding on weight and cardiometabolic health: a randomized controlled trial in adults with obesity
Time-restricted feeding (TRF) regimens have grown in popularity; however, very few studies
have examined their weight-loss efficacy. We conducted the first human trial (Clinicaltrials …
have examined their weight-loss efficacy. We conducted the first human trial (Clinicaltrials …
Intermittent fasting in the prevention and treatment of cancer
KK Clifton, CX Ma, L Fontana… - CA: a cancer journal for …, 2021 - Wiley Online Library
Chronic caloric restriction (CR) has powerful anticarcinogenic actions in both preclinical and
clinical studies but may be difficult to sustain. As an alternative to CR, there has been …
clinical studies but may be difficult to sustain. As an alternative to CR, there has been …
Cardiometabolic benefits of intermittent fasting
KA Varady, S Cienfuegos, M Ezpeleta… - Annual review of …, 2021 - annualreviews.org
This review aims to summarize the effects of intermittent fasting on markers of
cardiometabolic health in humans. All forms of fasting reviewed here—alternate-day fasting …
cardiometabolic health in humans. All forms of fasting reviewed here—alternate-day fasting …
Importance of circadian timing for aging and longevity
VA Acosta-Rodríguez, F Rijo-Ferreira, CB Green… - Nature …, 2021 - nature.com
Dietary restriction (DR) decreases body weight, improves health, and extends lifespan. DR
can be achieved by controlling how much and/or when food is provided, as well as by …
can be achieved by controlling how much and/or when food is provided, as well as by …
The ups and downs of caloric restriction and fasting: from molecular effects to clinical application
SJ Hofer, D Carmona‐Gutierrez, MI Mueller… - EMBO Molecular …, 2022 - embopress.org
Age‐associated diseases are rising to pandemic proportions, exposing the need for efficient
and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and …
and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and …
[HTML][HTML] Treatment of NAFLD with intermittent calorie restriction or low-carb high-fat diet–a randomised controlled trial
M Holmer, C Lindqvist, S Petersson… - JHEP Reports, 2021 - Elsevier
Background & Aims The first-line treatment for non-alcoholic fatty liver disease (NAFLD) is
weight reduction. Several diets have been proposed, with various effects specifically on liver …
weight reduction. Several diets have been proposed, with various effects specifically on liver …
Intermittent fasting in cardiovascular disorders—an overview
B Malinowski, K Zalewska, A Węsierska… - Nutrients, 2019 - mdpi.com
Intermittent fasting is a form of time restricted eating (typically 16 h fasting and 8 h eating),
which has gained popularity in recent years and shows promise as a possible new …
which has gained popularity in recent years and shows promise as a possible new …