Nasopharyngeal carcinoma: an evolving paradigm

KCW Wong, EP Hui, KW Lo, WKJ Lam… - Nature reviews Clinical …, 2021 - nature.com
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …

MRI detection of suspected nasopharyngeal carcinoma: a systematic review and meta-analysis

VV Gorolay, NN Niles, YR Huo, N Ahmadi… - Neuroradiology, 2022 - Springer
Purpose Endoscopic biopsy is recommended for diagnosis of nasopharyngeal carcinoma
(NPC). A proportion of lesions are hidden from endoscopic view but detected with magnetic …

Recommendations for Epstein-Barr virus–based screening for nasopharyngeal cancer in high-and intermediate-risk regions

WKJ Lam, AD King, JA Miller, Z Liu… - JNCI: Journal of the …, 2023 - academic.oup.com
A meeting of experts was held in November 2021 to review and discuss available data on
performance of Epstein-Barr virus (EBV)–based approaches to screen for early stage …

Convolutional neural network for discriminating nasopharyngeal carcinoma and benign hyperplasia on MRI

LM Wong, AD King, QYH Ai, WKJ Lam, DMC Poon… - European …, 2021 - Springer
Objectives A convolutional neural network (CNN) was adapted to automatically detect early-
stage nasopharyngeal carcinoma (NPC) and discriminate it from benign hyperplasia on a …

Comparison of new magnetic resonance imaging grading system with conventional endoscopy for the early detection of nasopharyngeal carcinoma

Z Liu, H Li, KJ Yu, SH Xie, AD King, QYH Ai, WJ Chen… - Cancer, 2021 - Wiley Online Library
Background Although stratifying individuals with respect to nasopharyngeal carcinoma
(NPC) risk with Epstein‐Barr virus–based markers is possible, the performance of diagnostic …

Clinical characteristics and predictive outcomes of recurrent nasopharyngeal carcinoma—a lingering pitfall of the long latency

YH Chen, SD Luo, SC Wu, CN Wu, TJ Chiu, YM Wang… - Cancers, 2022 - mdpi.com
Simple Summary Unlike other head and neck cancers, nasopharyngeal carcinoma (NPC)
with long-latent recurrence (> five years) is not rare. This study aims to investigate the …

The utility of texture analysis based on quantitative synthetic magnetic resonance imaging in nasopharyngeal carcinoma: a preliminary study

F Yang, Y Li, X Li, X Yu, Y Zhao, L Li, L Xie, M Lin - BMC Medical Imaging, 2023 - Springer
Background Magnetic resonance imaging (MRI) is commonly used for the diagnosis of
nasopharyngeal carcinoma (NPC) and occipital clivus (OC) invasion, but a proportion of …

Investigating the value of arterial spin labeling and intravoxel incoherent motion imaging on diagnosing nasopharyngeal carcinoma in T1 stage

Y Li, X Li, X Yu, M Lin, H Ouyang, L Xie, Y Shang - Cancer Imaging, 2020 - Springer
Background To investigate the diagnostic value of arterial spin labeling (ASL) and intravoxel
incoherent motion (IVIM) imaging in distinguishing nasopharyngeal carcinoma (NPC) in T1 …

Intravoxel incoherent motion diffusion-weighted imaging for discrimination of benign and malignant retropharyngeal nodes

TY So, QYH Ai, WKJ Lam, S Qamar, DMC Poon… - Neuroradiology, 2020 - Springer
Purpose Anatomical imaging criteria for the diagnosis of malignant head and neck nodes
may not always be reliable. This study aimed to evaluate the diagnostic value of …

Early detection of nasopharyngeal carcinoma: performance of a short contrast-free screening magnetic resonance imaging

AD King, QYH Ai, WKJ Lam, IOL Tse… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Although contrast-enhanced magnetic resonance imaging (MRI) detects early-
stage nasopharyngeal carcinoma (NPC) not detected by endoscopic-guided biopsy (EGB) …