Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Neuroinflammation is proposed as one of the mechanisms by which Alzheimer's disease
pathology, including amyloid-β plaques, leads to neuronal death and dysfunction. Increases …

Circadian rhythms are physiological and behavioural cycles generated by an endogenous
biological clock, the suprachiasmatic nucleus. The circadian system influences the majority …

We present the first three-dimensional (3D) concordance maps of cyto-and fiber architecture
of the human brain, combining histology, immunohistochemistry, and 7-T quantitative …

An overview of miRNAs altered in Alzheimer's disease (AD) was established by profiling the
hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing …

Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by the
loss of memory, multiple cognitive impairments and changes in the personality and …

The valproic acid (VPA) animal model of autism spectrum disorder (ASD) is one of the most
widely used animal model in the field. Like any other disease models, it can't model the …

Sleep–wake disturbances are a highly prevalent and often disabling feature of Alzheimer's
disease (AD). A cardinal feature of AD includes the formation of amyloid plaques, associated …

Introduction Sleep-wake disturbances are a common and early feature in Alzheimer's
disease (AD). The impact of early tau pathology in wake-promoting neurons (WPNs) …

The neurotransmitter histamine receives less attention compared with other biogenic
amines, because of its moderate action in the central nervous system (CNS). However …