Circadian rhythms in neurodegenerative disorders
M Nassan, A Videnovic - Nature Reviews Neurology, 2022 - nature.com
Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …
circadian rhythms that synchronize physiological and behavioural functions in humans. The …
Markers of microglia in post-mortem brain samples from patients with Alzheimer's disease: a systematic review
KE Hopperton, D Mohammad, MO Trépanier… - Molecular …, 2018 - nature.com
Neuroinflammation is proposed as one of the mechanisms by which Alzheimer's disease
pathology, including amyloid-β plaques, leads to neuronal death and dysfunction. Increases …
pathology, including amyloid-β plaques, leads to neuronal death and dysfunction. Increases …
'The clocks that time us'—circadian rhythms in neurodegenerative disorders
Circadian rhythms are physiological and behavioural cycles generated by an endogenous
biological clock, the suprachiasmatic nucleus. The circadian system influences the majority …
biological clock, the suprachiasmatic nucleus. The circadian system influences the majority …
A unified 3D map of microscopic architecture and MRI of the human brain
We present the first three-dimensional (3D) concordance maps of cyto-and fiber architecture
of the human brain, combining histology, immunohistochemistry, and 7-T quantitative …
of the human brain, combining histology, immunohistochemistry, and 7-T quantitative …
Alteration of the micro RNA network during the progression of Alzheimer's disease
An overview of miRNAs altered in Alzheimer's disease (AD) was established by profiling the
hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing …
hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing …
Therapeutics of neurotransmitters in Alzheimer's disease
R Kandimalla, PH Reddy - Journal of Alzheimer's Disease, 2017 - content.iospress.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by the
loss of memory, multiple cognitive impairments and changes in the personality and …
loss of memory, multiple cognitive impairments and changes in the personality and …
[HTML][HTML] Exploring the validity of valproic acid animal model of autism
DFN Mabunga, ELT Gonzales, J Kim… - Experimental …, 2015 - ncbi.nlm.nih.gov
The valproic acid (VPA) animal model of autism spectrum disorder (ASD) is one of the most
widely used animal model in the field. Like any other disease models, it can't model the …
widely used animal model in the field. Like any other disease models, it can't model the …
The sleep–wake cycle and Alzheimer's disease: what do we know?
Sleep–wake disturbances are a highly prevalent and often disabling feature of Alzheimer's
disease (AD). A cardinal feature of AD includes the formation of amyloid plaques, associated …
disease (AD). A cardinal feature of AD includes the formation of amyloid plaques, associated …
Profound degeneration of wake-promoting neurons in Alzheimer's disease
J Oh, RA Eser, AJ Ehrenberg, D Morales… - Alzheimer's & …, 2019 - Elsevier
Introduction Sleep-wake disturbances are a common and early feature in Alzheimer's
disease (AD). The impact of early tau pathology in wake-promoting neurons (WPNs) …
disease (AD). The impact of early tau pathology in wake-promoting neurons (WPNs) …
The roles of histamine and its receptor ligands in central nervous system disorders: An update
W Hu, Z Chen - Pharmacology & therapeutics, 2017 - Elsevier
The neurotransmitter histamine receives less attention compared with other biogenic
amines, because of its moderate action in the central nervous system (CNS). However …
amines, because of its moderate action in the central nervous system (CNS). However …