Mitochondrial heterogeneity in diseases
L Chen, M Zhou, H Li, D Liu, P Liao, Y Zong… - … and Targeted Therapy, 2023 - nature.com
As key organelles involved in cellular metabolism, mitochondria frequently undergo
adaptive changes in morphology, components and functions in response to various …
adaptive changes in morphology, components and functions in response to various …
The role of short-chain fatty acids in inflammatory skin diseases
X Xiao, X Hu, J Yao, W Cao, Z Zou, L Wang… - Frontiers in …, 2023 - frontiersin.org
Short-chain fatty acids (SCFAs) are metabolites of gut microbes that can modulate the host
inflammatory response, and contribute to health and homeostasis. Since the introduction of …
inflammatory response, and contribute to health and homeostasis. Since the introduction of …
The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence
A Hanaford, SC Johnson - Orphanet Journal of Rare Diseases, 2022 - Springer
Background Genetic mitochondrial diseases represent a significant challenge to human
health. These diseases are extraordinarily heterogeneous in clinical presentation and …
health. These diseases are extraordinarily heterogeneous in clinical presentation and …
S1P defects cause a new entity of cataract, alopecia, oral mucosal disorder, and psoriasis‐like syndrome
F Chen, C Ni, X Wang, R Cheng, C Pan… - EMBO Molecular …, 2022 - embopress.org
In this report, we discovered a new entity named cataract, alopecia, oral mucosal disorder,
and psoriasis‐like (CAOP) syndrome in two unrelated and ethnically diverse patients …
and psoriasis‐like (CAOP) syndrome in two unrelated and ethnically diverse patients …
Gut–microbiota–brain axis in the vulnerability to psychosis in adulthood after repeated cannabis exposure during adolescence
Increasing epidemiological evidence shows that the use of cannabis during adolescence
could increase the risk for psychosis in adulthood. However, the precise mechanisms …
could increase the risk for psychosis in adulthood. However, the precise mechanisms …
C-type lectin receptor expression is a hallmark of neutrophils infiltrating the skin in epidermolysis bullosa acquisita
CF Guerrero-Juarez, P Schilf, J Li, MP Zappia… - Frontiers in …, 2023 - frontiersin.org
Introduction Inflammatory epidermolysis bullosa acquisita (EBA) is characterized by a
neutrophilic response to anti-type VII collagen (COL7) antibodies resulting in the …
neutrophilic response to anti-type VII collagen (COL7) antibodies resulting in the …
Current knowledge in skin metabolomics: updates from literature review
A Paganelli, V Righi, E Tarentini… - International Journal of …, 2022 - mdpi.com
Metabolomic profiling is an emerging field consisting of the measurement of metabolites in a
biological system. Since metabolites can vary in relation to different stimuli, specific …
biological system. Since metabolites can vary in relation to different stimuli, specific …
Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging
TC Wikramanayake, J Chéret, A Sevilla… - Expert opinion on …, 2022 - Taylor & Francis
Introduction The analysis of the role of the mitochondria in oxidative damage and skin aging
has been a significant aspect of dermatological research. Mitochondria generate most …
has been a significant aspect of dermatological research. Mitochondria generate most …
Independent and sensory human mitochondrial functions reflecting symbiotic evolution
GB Stefano, P Büttiker, S Weissenberger… - Frontiers in Cellular …, 2023 - frontiersin.org
The bacterial origin of mitochondria has been a widely accepted as an event that occurred
about 1.45 billion years ago and endowed cells with internal energy producing organelle …
about 1.45 billion years ago and endowed cells with internal energy producing organelle …
Mitochondrial DNA heteroplasmy as an informational reservoir dynamically linked to metabolic and immunological processes associated with COVID-19 neurological …
GB Stefano, RM Kream - Cellular and Molecular Neurobiology, 2022 - Springer
Mitochondrial DNA (mtDNA) heteroplasmy is the dynamically determined co-expression of
wild type (WT) inherited polymorphisms and collective time-dependent somatic mutations …
wild type (WT) inherited polymorphisms and collective time-dependent somatic mutations …