Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

Temporally and spatially controlled activation of the Aurora A kinase (AURKA) regulates
centrosome maturation, entry into mitosis, formation and function of the bipolar spindle, and …

Local translation allows spatial control of gene expression. Here, we performed a dual
protein-mRNA localization screen, using smFISH on 523 human cell lines expressing GFP …

RNA-binding proteins (RBPs) have roles in the regulation of many post-transcriptional steps
in gene expression, but relatively few RBPs have been systematically studied. We searched …

The mRNAs stored in oocytes undergo general decay during the maternal-zygotic transition
(MZT), and their stability is tightly interconnected with meiotic cell-cycle progression …

Translation and mRNA degradation are affected by a key transition where eukaryotic
mRNAs exit translation and assemble an mRNP state that accumulates into processing …

Nearly two decades ago, Xenopus oocytes were found to contain mRNAs harboring a small
sequence in their 3′ untranslated regions that control cytoplasmic polyadenylation and …

The translational regulation of specific mRNAs is important for controlling gene expression.
The past few years have seen a rapid expansion in the identification and characterization of …

The regulated translation of messenger RNA is essential for cell-cycle progression,
establishment of the body plan during early development, and modulation of key activities in …

Local translation allows for a spatial control of gene expression. Here, we use high-
throughput smFISH to screen centrosomal protein-coding genes, and we describe 8 human …