Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations
We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …
Oxidative stress and male infertility
T Takeshima, K Usui, K Mori, T Asai… - Reproductive …, 2021 - Wiley Online Library
Abstract Background Between 30% and 80% of patients with male infertility produce
excessive reactive oxygen species (ROS) in their ejaculate even though the cause of male …
excessive reactive oxygen species (ROS) in their ejaculate even though the cause of male …
[HTML][HTML] Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios
A Agarwal, A Majzoub, SC Esteves, E Ko… - Translational …, 2016 - ncbi.nlm.nih.gov
Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for
male fertility evaluation. While its detrimental implications on sperm function were …
male fertility evaluation. While its detrimental implications on sperm function were …
Intracytoplasmic sperm injection for male infertility and consequences for offspring
Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …
[HTML][HTML] Sperm oxidative stress during in vitro manipulation and its effects on sperm function and embryo development
R Gualtieri, G Kalthur, V Barbato, S Longobardi… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …
Role of genetics and epigenetics in male infertility
S Gunes, SC Esteves - Andrologia, 2021 - Wiley Online Library
Male infertility is a complex condition with a strong genetic and epigenetic background. This
review discusses the importance of genetic and epigenetic factors in the pathophysiology of …
review discusses the importance of genetic and epigenetic factors in the pathophysiology of …
[HTML][HTML] Reproductive outcomes of testicular versus ejaculated sperm for intracytoplasmic sperm injection among men with high levels of DNA fragmentation in semen …
Objective To compare sperm DNA fragmentation (SDF) levels between testicular and
ejaculated sperm and to evaluate outcomes of intracytoplasmic sperm injection (ICSI) with …
ejaculated sperm and to evaluate outcomes of intracytoplasmic sperm injection (ICSI) with …
Oxidative stress in the pathophysiology of male infertility
C Ritchie, EY Ko - Andrologia, 2021 - Wiley Online Library
The effects of reactive oxygen species on male fertility are governed by the oxidative
paradox, defined by a delicate balance between oxidative stress and antioxidant capacity …
paradox, defined by a delicate balance between oxidative stress and antioxidant capacity …
An update on clinical and surgical interventions to reduce sperm DNA fragmentation in infertile men
Background Sperm chromatin integrity is essential for normal embryo development and
pregnancy outcome. Sperm DNA fragmentation (SDF) testing constitutes a diagnostic tool to …
pregnancy outcome. Sperm DNA fragmentation (SDF) testing constitutes a diagnostic tool to …