Human cytochrome P450 1A1 (hCYP1A1) has been an object of study due to its role in
precarcinogen metabolism; for this reason it is relevant to know more in depth the …

Histone deacetylase (HDAC) inhibitors are a group of anticancer drugs which cause growth
arrest and apoptosis of several tumor cells. HDAC inhibitors have been also found to …

Controlling both growth and differentiation of stem cells and their differentiated somatic
progeny is a challenge in numerous fields, from preclinical drug development to clinical …

Butyrate, a short-chain fatty acid produced by fermentation of dietary fiber, is an important
regulator of colonic epithelium homeostasis. In this study, we investigated the impact of this …

Histone deacetylase (HDAC) inhibitors are becoming a novel and promising class of
antineoplastic agents that have been used for cancer therapy in the clinic. Two HDAC …

In vivo application of histone deacetylase (HDAC) inhibitor trichostatin‐A (TSA) in mice
results in male infertility. To get more insight into the mechanisms underlying this …

Histone deacetylase inhibitors (HDI) have been shown to increase differentiation-related
gene expression in several tumor-derived cell lines by hyperacetylating core histones …

Abstract TaqMan Gene Expression assays were used to profile the mRNA expression of
estrogen receptor (ERα and ERβ) and estrogen metabolism enzymes including cytosolic …

Histone deacetylase inhibitors such as valproic acid (VPA) and trichostatin A (TSA) were
shown to exert antitumor activity. Here, the toxicity of both drugs to human neuroblastoma …

Valproic acid (VPA) is well‐known as a histone deacetylase (HDAC) inhibitor. It has been
reported that HDAC inhibitors enhance basal and aryl hydrocarbon receptor (AhR) ligand …