High drug-loading nanomedicines: progress, current status, and prospects

S Shen, Y Wu, Y Liu, D Wu - International journal of nanomedicine, 2017 - Taylor & Francis
Drug molecules transformed into nanoparticles or endowed with nanostructures with or
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …

Nano‐star‐shaped polymers for drug delivery applications

DP Yang, MNNL Oo, GR Deen, Z Li… - Macromolecular rapid …, 2017 - Wiley Online Library
With the advancement of polymer engineering, complex star‐shaped polymer architectures
can be synthesized with ease, bringing about a host of unique properties and applications …

Polymer nanomedicines

J Kopeček, J Yang - Advanced drug delivery reviews, 2020 - Elsevier
Polymer nanomedicines (macromolecular therapeutics, polymer-drug conjugates, drug-free
macromolecular therapeutics) are a group of biologically active compounds that are …

Fluorescence optical imaging in anticancer drug delivery

T Etrych, H Lucas, O Janoušková, P Chytil… - Journal of Controlled …, 2016 - Elsevier
In the past several decades, nanosized drug delivery systems with various targeting
functions and controlled drug release capabilities inside targeted tissues or cells have been …

The light at the end of the tunnel—second generation HPMA conjugates for cancer treatment

J Yang, J Kopeček - Current opinion in colloid & interface science, 2017 - Elsevier
It is almost four decades since N-(2-hydroxypropyl) methacrylamide (HPMA)-based
copolymers arose as drug carriers. Although fundamentals have been established and …

Prodrugs for targeted cancer therapy

C Souza, DS Pellosi, AC Tedesco - Expert review of anticancer …, 2019 - Taylor & Francis
Introduction: Prodrugs have been used to improve the selectivity and efficacy of cancer
therapy by targeting unique abnormal markers that are overexpressed by cancer cells and …

Dendrimer prodrugs

S da Silva Santos, E Igne Ferreira, J Giarolla - Molecules, 2016 - mdpi.com
The main objective of this review is to describe the importance of dendrimer prodrugs in the
design of new drugs, presenting numerous applications of these nanocomposites in the …

Fluorescence imaging as a tool in preclinical evaluation of polymer-based nano-DDS systems intended for cancer treatment

T Etrych, O Janoušková, P Chytil - Pharmaceutics, 2019 - mdpi.com
Targeted drug delivery using nano-sized carrier systems with targeting functions to
malignant and inflammatory tissue and tailored controlled drug release inside targeted …

Current trends in the development of HPMA-based block copolymeric nanoparticles for their application in drug delivery

Y Bobde, S Biswas, B Ghosh - European Polymer Journal, 2020 - Elsevier
Abstract N-(2-hydroxypropyl) methacrylamide-based block copolymers (pHPMA) have
received attention due to their hydrophilicity, non-immunogenicity, biocompatibility and …

[HTML][HTML] Overcoming resistance to rituximab in relapsed non-Hodgkin lymphomas by antibody-polymer drug conjugates actively targeted by anti-CD38 daratumumab

O Lidický, P Klener, D Machová, P Vočková… - Journal of controlled …, 2020 - Elsevier
B-cell non-Hodgkin lymphomas (B-NHL) represent the most common type of hematologic
malignancies in the Western hemisphere. The therapy of all B-NHL is based on the …