Posttraumatic stress disorder: from gene discovery to disease biology
R Polimanti, FR Wendt - Psychological medicine, 2021 - cambridge.org
Posttraumatic stress disorder (PTSD) is a complex mental disorder afflicting approximately
7% of the population. The diverse number of traumatic events and the wide array of …
7% of the population. The diverse number of traumatic events and the wide array of …
Evolutionary conserved role of neural cell adhesion molecule-1 in memory
V Vukojevic, P Mastrandreas, A Arnold, F Peter… - Translational …, 2020 - nature.com
The neural cell adhesion molecule 1 (NCAM-1) has been implicated in several brain-related
biological processes, including neuronal migration, axonal branching, fasciculation, and …
biological processes, including neuronal migration, axonal branching, fasciculation, and …
The effect of fampridine on working memory: a randomized controlled trial based on a genome-guided repurposing approach
A Papassotiropoulos, V Freytag, N Schicktanz… - Molecular …, 2024 - nature.com
Working memory (WM), a key component of cognitive functions, is often impaired in
psychiatric disorders such as schizophrenia. Through a genome-guided drug repurposing …
psychiatric disorders such as schizophrenia. Through a genome-guided drug repurposing …
Transcriptional signal and cell specificity of genes related to cortical structural differences of post-traumatic stress disorder
Due to the diversity of traumatic events, the diagnosis of Post-traumatic Stress Disorder is
heterogeneous. The pathogenesis has been explored in the fields of brain imaging and …
heterogeneous. The pathogenesis has been explored in the fields of brain imaging and …
[HTML][HTML] Predicting emotional arousal and emotional memory performance from an identical brain network
E Loos, T Egli, D Coynel, M Fastenrath, V Freytag… - NeuroImage, 2019 - Elsevier
Encoding and retrieval of emotionally arousing stimuli depend on the activation of multiple
interconnected brain regions, with people showing differences in their individual strength of …
interconnected brain regions, with people showing differences in their individual strength of …
Identification of a unique, de novo MYCBP2 variant in an individual with highly superior autobiographical memory
A Papassotiropoulos, J Petrovska, A Arnold, A LePort… - medRxiv, 2024 - medrxiv.org
Highly Superior Autobiographical Memory (HSAM) is an extremely rare condition
characterized by an individual's unparallelled ability to recall personal past events with …
characterized by an individual's unparallelled ability to recall personal past events with …
NTRK2 methylation is related to reduced PTSD risk in two African cohorts of trauma survivors
V Vukojevic, D Coynel, NR Ghaffari… - Proceedings of the …, 2020 - National Acad Sciences
Extensive pharmacologic, genetic, and epigenetic research has linked the glucocorticoid
receptor (GR) to memory processes, and to risk and symptoms of posttraumatic stress …
receptor (GR) to memory processes, and to risk and symptoms of posttraumatic stress …
[HTML][HTML] Recognition memory performance can be estimated based on brain activation networks
J Petrovska, E Loos, D Coynel, T Egli… - Behavioural Brain …, 2021 - Elsevier
Background Recognition memory is an essential ability for functioning in everyday life.
Establishing robust brain networks linked to recognition memory performance can help to …
Establishing robust brain networks linked to recognition memory performance can help to …
Biomolecular vulnerability factors of mental disorders: Influence of chronic and traumatic stress on the immune system, free radicals and mitochondria
M Hitzler, A Karabatsiakis, IT Kolassa - Psychotherapeut, 2019 - Springer
Chronic and traumatic stress are both central risk factors for mental disorders and also
physical diseases. The underlying psychobiological processes contributing to the increased …
physical diseases. The underlying psychobiological processes contributing to the increased …
Ayurgenomics-based frameworks in precision and integrative medicine: Translational opportunities
M Mukerji - Cambridge Prisms: Precision Medicine, 2023 - cambridge.org
In today's globalized and flat world, a patient can access and seek multiple health and
disease management options. A digitally enabled participatory framework that allows an …
disease management options. A digitally enabled participatory framework that allows an …