Viruses infect all kingdoms of life; their genomes vary from DNA to RNA and in size from 2kB
to 1 MB or more. Viruses frequently employ disordered proteins, that is, protein products of …

Human history is inextricably linked to the introduction of desirable heritable traits in plants
and animals. Selective breeding (SB) predates our historical period and has been practiced …

Histone deacetylases (HDACs) play a crucial role in transcriptional regulation and are
implicated in various diseases, including cancer. They are involved in histone tail …

Organismal physiology is widely regulated by the molecular circadian clock, a feedback loop
composed of protein complexes whose members are enriched in intrinsically disordered …

Viruses and their hosts are involved in an 'arms race'where they continually evolve
mechanisms to overcome each other. It has long been proposed that intrinsic disorder …

Human cytomegalovirus (HCMV) is an opportunistic pathogen that infects a majority of the
world population. It may cause severe disease in immunocompromised people and lead to …

Abstract The human papillomavirus (HPV)-18 E7 (E7) oncoprotein is a major transforming
protein that is thought to be involved in the development of cervical cancer. It is well-known …

The retinoblastoma tumor suppressor (Rb) is a multifunctional protein that primarily
regulates the cell cycle but also has roles in cellular differentiation, DNA damage response …