[HTML][HTML] Nuclear medicine imaging in neuroblastoma: current status and new developments

A Samim, GAM Tytgat, G Bleeker, STM Wenker… - Journal of Personalized …, 2021 - mdpi.com
Neuroblastoma is the most common extracranial solid malignancy in children. At diagnosis,
approximately 50% of patients present with metastatic disease. These patients are at high …

[HTML][HTML] Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements

X Chen, T Kudo, C Lapa, A Buck, T Higuchi - Journal of Neural …, 2020 - Springer
The norepinephrine transporter (NET) is a major target for the evaluation of the cardiac
sympathetic nerve system in patients with heart failure and Parkinson's disease. It is also …

68Ga-DOTATATE and 123I-mIBG as imaging biomarkers of disease localisation in metastatic neuroblastoma: implications for molecular radiotherapy

JE Gains, MD Aldridge, MV Mattoli… - Nuclear Medicine …, 2020 - journals.lww.com
Purpose Iodine-131-labelled meta-iodobenzylguanidine (131 I-mIBG) and lutetium-177-
labelled DOTATATE (177 Lu-DOTATATE) are used for molecular radiotherapy of metastatic …

Hypervalent iodine mediated chemoselective iodination of alkynes

Y Liu, D Huang, J Huang… - The Journal of Organic …, 2017 - ACS Publications
Reported herein are practical approaches for the chemoselective mono-, di-, and tri-
iodination of alkynes based on efficient oxidative iodinations catalyzed by hypervalent …

New horizons in cardiac innervation imaging: introduction of novel 18F-labeled PET tracers

R Kobayashi, X Chen, RA Werner, C Lapa… - European journal of …, 2017 - Springer
Cardiac sympathetic nervous activity can be uniquely visualized by non-invasive
radionuclide imaging techniques due to the fast growing and widespread application of …

Radiolabeling of DNA bipyramid and preliminary biological evaluation in mice

J Li, D Jiang, B Bao, Y He, L Liu… - Bioconjugate chemistry, 2016 - ACS Publications
Self-assembled DNA nanostructures, as a new type of nanocarriers, have shown great
potential in molecular imaging probes. DNA bipyramid nanostructures (DBNs), as a classic …

[HTML][HTML] Initial evaluation of AF78: a rationally designed fluorine-18-labelled PET radiotracer targeting norepinephrine transporter

X Chen, A Fritz, RA Werner, N Nose, Y Yagi… - Molecular Imaging and …, 2020 - Springer
Purpose Taking full advantage of positron emission tomography (PET) technology, fluorine-
18-labelled radiotracers targeting norepinephrine transporter (NET) have potential …

Small molecule PET tracers for transporter imaging

MR Kilbourn - Seminars in Nuclear Medicine, 2017 - Elsevier
As the field of PET has expanded and an ever-increasing number and variety of compounds
have been radiolabeled as potential in vivo tracers of biochemistry, transporters have …

Radiolabeled (4-Fluoro-3-Iodobenzyl) Guanidine Improves Imaging and Targeted Radionuclide Therapy of Norepinephrine Transporter–Expressing Tumors

A Yamaguchi, H Hanaoka, T Higuchi… - Journal of Nuclear …, 2018 - Soc Nuclear Med
18F-or 131I-labeled (4-fluoro-3-iodobenzyl) guanidine (FIBG) has been a promising yet
unattainable derivative of radioiodine-labeled meta-iodobenzylguanidine (MIBG), because …

[HTML][HTML] Harnessing ionic interactions and hydrogen bonding for nucleophilic fluorination

YH Oh, H Choi, C Park, DW Kim, S Lee - Molecules, 2020 - mdpi.com
We review recent works for nucleophilic fluorination of organic compounds in which the
Coulombic interactions between ionic species and/or hydrogen bonding affect the outcome …