Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …

Neuroinflammation commences decades before Alzheimer's disease (AD) clinical onset and
represents one of the earliest pathomechanistic alterations throughout the AD continuum …

Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …

Alzheimer's disease (AD) is the most common cause of dementia, accounting for more than
50 million patients worldwide. Current evidence suggests the exact mechanism behind this …

Carnosine is a natural endogenous dipeptide widely distributed in mammalian tissues,
existing at particularly high concentrations in the muscles and brain and possesses well …

Depression is a risk factor for the development of Alzheimer's disease (AD). A
neurobiological and clinical continuum exists between AD and depression, with …

Background TREM2 is a microglial cell surface receptor, with risk mutations linked to
Alzheimer's disease (AD), including R47H. TREM2 signalling via SYK aids phagocytosis …

A dysregulation of the wound healing process can lead to the development of various
intractable ulcers or excessive scar formation. Therefore it is essential to identify novel …

The current 2019 novel coronavirus disease (COVID-19), an emerging infectious disease, is
undoubtedly the most challenging pandemic in the 21st century. A total of 92,977,768 …

Objectives: Vortioxetine has already shown its efficacy in the acute and long-term treatment
of major depressive disorder (MDD) and its potential interest in the prevention of relapse …