[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Insulin resistance and atherosclerosis: implications for insulin-sensitizing agents

A Di Pino, RA DeFronzo - Endocrine reviews, 2019 - academic.oup.com
Patients with type 2 diabetes mellitus (T2DM) are at high risk for macrovascular
complications, which represent the major cause of mortality. Despite effective treatment of …

Local and systemic effects of the multifaceted epicardial adipose tissue depot

G Iacobellis - Nature Reviews Endocrinology, 2015 - nature.com
Epicardial adipose tissue is a unique and multifaceted fat depot with local and systemic
effects. This tissue is distinguished from other visceral fat depots by a number of anatomical …

Body fat distribution and risk of cardiovascular disease: an update

JP Després - Circulation, 2012 - Am Heart Assoc
Epidemiological, clinical, and mechanistic preclinical studies conducted in the field of
cardiovascular medicine have led to remarkable progress in our understanding of …

Epicardial adipose tissue: clinical biomarker of cardio-metabolic risk

AC Villasante Fricke, G Iacobellis - International journal of molecular …, 2019 - mdpi.com
Epicardial adipose tissue (EAT) is part of the visceral adipose tissue (VAT) that surrounds
the heart and it is a quantifiable, modifiable, and multifaceted tissue that has both local and …

Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features

G Iacobellis, AC Bianco - Trends in Endocrinology & Metabolism, 2011 - cell.com
Epicardial adipose tissue is an unusual visceral fat depot with anatomical and functional
contiguity to the myocardium and coronary arteries. Under physiological conditions …

Echocardiographic epicardial fat: a review of research and clinical applications

G Iacobellis, HJ Willens - Journal of the American Society of …, 2009 - Elsevier
Epicardial fat plays a role in cardiovascular diseases. Because of its anatomic and functional
proximity to the myocardium and its intense metabolic activity, some interactions between …

Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor?

LS Bhatia, NP Curzen, PC Calder… - European heart …, 2012 - academic.oup.com
Non-alcoholic fatty liver disease (NAFLD) affects up to a third of the population worldwide
and may confer increased cardiometabolic risk with consequent adverse cardiovascular …

Pericardial fat and the risk of heart failure

S Kenchaiah, J Ding, JJ Carr, MA Allison… - Journal of the American …, 2021 - jacc.org
Background Obesity is a well-established risk factor for heart failure (HF). However,
implications of pericardial fat on incident HF is unclear. Objectives This study sought to …

Age-related changes in total and regional fat distribution

JL Kuk, TJ Saunders, LE Davidson, R Ross - Ageing research reviews, 2009 - Elsevier
Aging is associated with progressive changes in total and regional fat distribution that have
negative health consequences. Indeed, a preferential increase in abdominal fat, in particular …