Tonic and burst-like locus coeruleus stimulation distinctly shift network activity across the cortical hierarchy

C Grimm, SN Duss, M Privitera, BR Munn… - Nature …, 2024 - nature.com
Noradrenaline (NA) release from the locus coeruleus (LC) changes activity and connectivity
in neuronal networks across the brain, modulating multiple behavioral states. NA release is …

[HTML][HTML] A functional account of stimulation-based aerobic glycolysis and its role in interpreting BOLD signal intensity increases in neuroimaging experiments

JE Theriault, C Shaffer, GA Dienel, CY Sander… - Neuroscience & …, 2023 - Elsevier
In aerobic glycolysis, oxygen is abundant, and yet cells metabolize glucose without using it,
decreasing their ATP per glucose yield by 15-fold. During task-based stimulation, aerobic …

Distal activity patterns shape the spatial specificity of neurovascular coupling

É Martineau, A Malescot, N Elmkinssi… - Nature …, 2024 - nature.com
Neurovascular coupling links brain activity to local changes in blood flow, forming the basis
for non-invasive brain mapping. Using multiscale imaging, we investigated how vascular …

Evidence for the involvement of the Tachykinin NK1 Receptor in Acute Inflammation of the Central Nervous System

RJ Turner, AJ Nimmo - Receptors, 2023 - mdpi.com
Neuroinflammation is considered to be a significant component in a range of
neuropathologies. Unfortunately, whilst its role is well recognised, the options for therapeutic …

Rat superior colliculus encodes the transition between static and dynamic vision modes

R Gil, M Valente, N Shemesh - Nature Communications, 2024 - nature.com
The visual continuity illusion involves a shift in visual perception from static to dynamic vision
modes when the stimuli arrive at high temporal frequency, and is critical for recognizing …

Distinct neurochemical influences on fMRI response polarity in the striatum

DH Cerri, DL Albaugh, LR Walton, B Katz… - Nature …, 2024 - nature.com
The striatum, known as the input nucleus of the basal ganglia, is extensively studied for its
diverse behavioral roles. However, the relationship between its neuronal and vascular …

[HTML][HTML] Impact of environmental enrichment on the GABAergic neurons and glucocorticoid receptors in the hippocampus and nucleus accumbens of Wistar rats: Pro …

A Begega, CI Jove, M López, RD Moreno - Brain Research Bulletin, 2023 - Elsevier
The unpredictable chronic mild stress (UCMS) model has been used to induce depressive-
like symptoms in animal models. Our work aims to evaluate the impact of environmental …

Long-range inhibitory neurons mediate cortical neurovascular coupling

CF Ruff, FJ Anaya, SJ Dienel, A Rakymzhan… - Cell reports, 2024 - cell.com
To meet the high energy demands of brain function, cerebral blood flow (CBF) parallels
changes in neuronal activity by a mechanism known as neurovascular coupling (NVC) …

[HTML][HTML] Disparity in temporal and spatial relationships between resting-state electrophysiological and fMRI signals

W Tu, SR Cramer, N Zhang - Research Square, 2024 - ncbi.nlm.nih.gov
Resting-state brain networks (RSNs) have been widely applied in health and disease, but
the interpretation of RSNs in terms of the underlying neural activity is unclear. To address …

Serotonergic regulation of cortical neurovascular coupling and hemodynamics upon awakening from sleep in mice

A Natsubori, S Kwon, Y Honda… - Journal of Cerebral …, 2024 - journals.sagepub.com
Neurovascular coupling (NVC) is the functional hyperemia of the brain responding to local
neuronal activity. It is mediated by astrocytes and affected by subcortical ascending …