IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains
MP Lefranc, C Pommié, M Ruiz, V Giudicelli… - Developmental & …, 2003 - Elsevier
IMGT, the international ImMunoGeneTics database (http://imgt. cines. fr) is a high quality
integrated information system specializing in immunoglobulins (IG), T cell receptors (TR) …
integrated information system specializing in immunoglobulins (IG), T cell receptors (TR) …
γδ T cells: functional plasticity and heterogeneity
SR Carding, PJ Egan - Nature reviews immunology, 2002 - nature.com
Abstract γδ T cells remain an enigma. They are capable of generating more unique antigen
receptors than αβ T cells and B cells combined, yet their repertoire of antigen receptors is …
receptors than αβ T cells and B cells combined, yet their repertoire of antigen receptors is …
Intranasal priming induces local lung-resident B cell populations that secrete protective mucosal antiviral IgA
Antibodies secreted at the mucosal surface play an integral role in immune defense by
serving to neutralize the pathogen and promote its elimination at the site of entry. Secretory …
serving to neutralize the pathogen and promote its elimination at the site of entry. Secretory …
[HTML][HTML] Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms
Individuals with coronavirus disease 2019 (COVID-19) frequently develop neurological
symptoms, but the biological underpinnings of these phenomena are unknown. Through …
symptoms, but the biological underpinnings of these phenomena are unknown. Through …
Mucosal or systemic microbiota exposures shape the B cell repertoire
Colonization by the microbiota causes a marked stimulation of B cells and induction of
immunoglobulin, but mammals colonized with many taxa have highly complex and …
immunoglobulin, but mammals colonized with many taxa have highly complex and …
McPAS-TCR: a manually curated catalogue of pathology-associated T cell receptor sequences
N Tickotsky, T Sagiv, J Prilusky, E Shifrut… - …, 2017 - academic.oup.com
Motivation While growing numbers of T cell receptor (TCR) repertoires are being mapped by
high-throughput sequencing, existing methods do not allow for computationally connecting a …
high-throughput sequencing, existing methods do not allow for computationally connecting a …
[HTML][HTML] Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins
Assessment of single-cell gene expression (single-cell RNA sequencing) and adaptive
immune receptor (AIR) sequencing (scVDJ-seq) has been invaluable in studying …
immune receptor (AIR) sequencing (scVDJ-seq) has been invaluable in studying …
[HTML][HTML] Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
Broadly neutralizing antibodies (bNAbs) to HIV-1 can prevent infection and are therefore of
great importance for HIV-1 vaccine design. Notably, bNAbs are highly somatically mutated …
great importance for HIV-1 vaccine design. Notably, bNAbs are highly somatically mutated …
Programme of self-reactive innate-like T cell-mediated cancer immunity
Cellular transformation induces phenotypically diverse populations of tumour-infiltrating T
cells,,,–, and immune checkpoint blockade therapies preferentially target T cells that …
cells,,,–, and immune checkpoint blockade therapies preferentially target T cells that …
[HTML][HTML] A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding
Antibody-antigen binding relies on the specific interaction of amino acids at the paratope-
epitope interface. The predictability of antibody-antigen binding is a prerequisite for de novo …
epitope interface. The predictability of antibody-antigen binding is a prerequisite for de novo …