Wearable Clinic: From Microneedle‐Based Sensors to Next‐Generation Healthcare Platforms

H Sun, Y Zheng, G Shi, H Haick, M Zhang - Small, 2023 - Wiley Online Library
The rapid development of wearable biosensing calls for next‐generation devices that allow
continuous, real‐time, and painless monitoring of health status along with responsive …

Microneedle-based transdermal detection and sensing devices

J Wang, Z Lu, R Cai, H Zheng, J Yu, Y Zhang, Z Gu - Lab on a Chip, 2023 - pubs.rsc.org
Microneedles have been expected for the construction of next-generation biosensors
towards personalization, digitization, and intellectualization due to their metrics of minimal …

3D-printed microneedle-based potentiometric sensor for pH monitoring in skin interstitial fluid

M Parrilla, A Vanhooydonck, M Johns, R Watts… - Sensors and Actuators B …, 2023 - Elsevier
Wearable electrochemical sensors are driven by the user-friendly capability of continuous
monitoring of key biomarkers for diagnostic or therapeutic operations. Particularly …

Microneedle-based biosensing

LK Vora, AH Sabri, PE McKenna, A Himawan… - Nature Reviews …, 2024 - nature.com
Microneedles (MNs) are microscopic needles that are applied to the skin in a minimally
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …

Skin-interfaced electronics: A promising and intelligent paradigm for personalized healthcare

Y Zhu, J Li, J Kim, S Li, Y Zhao, J Bahari, P Eliahoo… - Biomaterials, 2023 - Elsevier
Skin-interfaced electronics (skintronics) have received considerable attention due to their
thinness, skin-like mechanical softness, excellent conformability, and multifunctional …

Microneedle biomedical devices

M Zheng, T Sheng, J Yu, Z Gu, C Xu - Nature Reviews Bioengineering, 2024 - nature.com
Microneedle (MN) technologies have gained interest for biomedical applications, ranging
from drug delivery to sensing and tissue sampling in skin and internal organs. The …

Interstitial fluid-based wearable biosensors for minimally invasive healthcare and biomedical applications

Z Wu, Z Qiao, S Chen, S Fan, Y Liu, J Qi… - Communications …, 2024 - nature.com
Interstitial fluid (ISF), a biological fluid rich in diverse biomarkers and analytes and similar to
blood composition, has garnered significant attention as a valuable source of clinically …

In vivo transdermal multi-ion monitoring with a potentiometric microneedle-based sensor patch

Á Molinero-Fernández, A Casanova, Q Wang… - ACS …, 2022 - ACS Publications
Microneedle sensor technology offers exciting opportunities for decentralized clinical
analyses. A novel issue puts forward herein is to demonstrate the uniqueness of membrane …

Recent advances in microneedle-based sensors for sampling, diagnosis and monitoring of chronic diseases

Ö Erdem, I Eş, GA Akceoglu, Y Saylan, F Inci - Biosensors, 2021 - mdpi.com
Chronic diseases (CDs) are noncommunicable illnesses with long-term symptoms
accounting for~ 70% of all deaths worldwide. For the diagnosis and prognosis of CDs …

Microneedle electrochemical aptamer-based sensing: Real-time small molecule measurements using sensor-embedded, commercially-available stainless steel …

AM Downs, A Bolotsky, BM Weaver, H Bennett… - Biosensors and …, 2023 - Elsevier
Microneedle sensors could enable minimally-invasive, continuous molecular monitoring–
informing on disease status and treatment in real-time. Wearable sensors for …