The natural history, pathobiology, and clinical manifestations of SARS-CoV-2 infections

J Machhi, J Herskovitz, AM Senan, D Dutta… - Journal of neuroimmune …, 2020 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
coronavirus disease 2019 (COVID-19). SARS-CoV-2, is a positive-sense single-stranded …

Coronavirus envelope protein: current knowledge

D Schoeman, BC Fielding - Virology journal, 2019 - Springer
Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and
mammals but, in the last few decades, have shown to be capable of infecting humans as …

New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

CA Devaux, JM Rolain, P Colson, D Raoult - International journal of …, 2020 - Elsevier
ABSTRACT Recently, a novel coronavirus (2019-nCoV), officially known as severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China. Despite drastic …

Evidence for gastrointestinal infection of SARS-CoV-2

F Xiao, M Tang, X Zheng, Y Liu, X Li, H Shan - Gastroenterology, 2020 - gastrojournal.org
Methods From February 1 to 14, 2020, clinical specimens, including serum,
nasopharyngeal, and oropharyngeal swabs; urine; stool; and tissues from 73 hospitalized …

The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles

B Boson, V Legros, B Zhou, E Siret, C Mathieu… - Journal of Biological …, 2021 - ASBMB
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a β-coronavirus, is the
causative agent of the COVID-19 pandemic. Like for other coronaviruses, its particles are …

A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

EJ Snijder, RWAL Limpens, AH de Wilde… - PLoS …, 2020 - journals.plos.org
Zoonotic coronavirus (CoV) infections, such as those responsible for the current severe
acute respiratory syndrome-CoV 2 (SARS-CoV-2) pandemic, cause grave international …

Human coronavirus: host-pathogen interaction

TS Fung, DX Liu - Annual review of microbiology, 2019 - annualreviews.org
Human coronavirus (HCoV) infection causes respiratory diseases with mild to severe
outcomes. In the last 15 years, we have witnessed the emergence of two zoonotic, highly …

Membrane binding proteins of coronaviruses

EA J Alsaadi, IM Jones - Future Virology, 2019 - Taylor & Francis
Coronaviruses (CoVs) infect many species causing a variety of diseases with a range of
severities. Their members include zoonotic viruses with pandemic potential where …

The coronavirus nucleocapsid is a multifunctional protein

R McBride, M Van Zyl, BC Fielding - Viruses, 2014 - mdpi.com
The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic
RNA, interacts with the viral membrane protein during virion assembly and plays a critical …

[HTML][HTML] Antivirals for COVID-19: a critical review

A Frediansyah, R Tiwari, K Sharun, K Dhama… - … and global health, 2021 - Elsevier
No specific drugs have been approved for coronavirus disease 2019 (COVID-19) to date as
the development of antivirals usually requires time. Therefore, assessment and use of …